These "recent wrongly-decided court decisions threaten to thrust the U.S. regulatory system for agriculture biotechnology into a non-functioning regulatory system," the letter said.
The senators charged that the plaintiffs manipulated the law to "circumvent sound science and the intent of Congress" in order to "slow regulatory decisions and prevent commercialization in the future."
The plaintiffs have included conventional farmers and environmental groups.
Sounding strong support for genetically modified crops, the senators said "the innovation and adoption of agriculture biotechnology has contributed to higher yields, greater production and increased profits for U.S. farmers."