Former President George W. Bush first appointed McDowell to the FCC in 2006, and he was re-appointed by President Obama in 2009.
He announced his intent to resign in March.
On the FCC, McDowell urged policymakers to battle international attempts to regulate the Internet and dissented from his Democratic colleagues on issues such as net neutrality regulations. He joined the Democrats in overhauling the multibillion dollar Universal Service Fund and moving to auction broadcast television frequencies to cellphone carriers.
FCC Chairman Julius Genachowski is also scheduled to step down this month. He plans to join the Aspen Institute as a senior fellow.
President Obama has nominated former lobbyist and technology investor Tom Wheeler to replace Genachowski as the agency's chairman, but he has yet to name McDowell's replacement.