Denis McDonough is expected to visit Senate Democrats for their weekly lunch on Thursday.
Senate Democrats have been slow to embrace the House's Veterans Affairs bill.
He urged lawmakers to coordinate the party's messaging, strategy.
The Wednesday evening meeting will address "shared priorities for 2014."
“There’s a lot of frustration, everywhere,” Sen. Dianne Feinstein (D-Calif.) said.
Centrist Dems say the chamber has become engulfed in partisan sniping during his tenure.
Politicians in both parties are turning to a familiar practice: blame the media.
Obama is separately meeting with Senate Democrats at their retreat next week.
Deal could let Senate Dems avoid having to vote on a budget in the midterm election year.