WATCH LIVE: Secretary of State Kerry holds first Google+ Hangout

The interactive discussion, titled "“The U.S. in the World: What’s in it for us?," will be moderated by NBC News Chief Foreign Affairs Correspondent Andrea Mitchell.

The online chat will build on Kerry’s "first major public address as Secretary of State at the University of Virginia, where he outlined to Americans the impact that our involvement abroad has here at home," said a statement released by the State Department.

During the February address, Kerry slammed his former congressional colleagues for opposing foreign aid.

"As a recovering politician, I can tell you that nothing gets a crowd clapping faster in a lot of places than saying: 'I'm going to Washington to get them to stop spending all that money over there.' " he said.

“If you're looking for an applause line, it's about as guaranteed an applause line as you can get. But guess what: It does nothing to guarantee our security. It does nothing to guarantee a stronger country. It doesn't guarantee a sounder economy or a more stable job market.”

Kerry is the first secretary of State to participate in this type of online conversation. Other members of the administration have used to format, including President Obama, Vice President Biden and first lady Michelle Obama.

Today's event kicks off the new online series, “Hangouts at State,” which will cover foreign policy issues like democracy promotion, human rights, counterterrorism efforts, economic development, climate change, and drug interdiction, according to the State Department.