The $300,000 ad campaign launched by the group Our Destiny PAC is expected to air across New Hampshire this weekend, according to The Associated Press.
The ad starts off by comparing Huntsman to the rest of the GOP presidential field.
"They've risen, they've fallen," a narrator says as images of former and current GOP candidates Tim Pawlenty, Michele Bachmann, Rick Perry, Herman Cain and Newt Gingrich appear on the screen.
"Till two serious candidates remained. One willing to say anything, be anything. One who can actually do the job," with photos of Romney and Huntsman respectively.
Throughout the primary process, Romney has remained at the top of the polls, as rivals Bachmann, Perry, Cain and Gingrich have all seen sharp rises in the polls followed by steep declines.
Pawlenty dropped out of the Republican contest in August after a disappointing showing in Iowa's Ames Straw Poll.
"He'll [Huntsman] make America strong. One state can stop the chameleon," concludes the voice in the ad with a photo of Romney on the screen.
Huntsman has bet his candidacy on winning New Hampshire and has said he believes the state offers his best chance of going on to win the nomination.
Huntsman has remained at the bottom of most national polls but has gained some traction in New Hampshire in recent weeks.
However, Romney held a commanding lead in a poll of likely New Hampshire Republican primary voters released Thursday by Public Policy Polling. Huntsman took 12 percent, placing him fourth in the poll.