The businesswoman, Clemson University administrator and sister of comedian Stephen Colbert is in a tight race with former South Carolina Gov. Mark Sanford (R) for the seat. The district leans Republican but Sanford's unfavorable numbers are very high due to his past marital infidelities, and Democrats believe they have a real shot at winning the seat in early May.
The big question of the race is whether Colbert Busch's self-portrayal as a fiscally conservative, independent businesswoman will hold up after Republicans seek to tie her to President Obama in a district where Obama won just 40 percent of the vote. Her first ad seeks to bolster that image.