"USA Today had a big, front-page feature on the new healthcare law and said that the opposition to ObamaCare is at an all-time high," Leno said. "In fact, it's gotten so bad the president is calling it 'BidenCare.'"
Leno added that Biden was in Iowa last weekend for a fundraiser, raising speculation he might run for president in 2016.
"Late Night" host Jimmy Fallon also joked about Biden's Iowa visit, but suggested the vice president never delivered a speech.
"Unfortunately, he missed giving his speech because he spent four hours trapped in a corn maze," Fallon said.