Donald TrumpDonald TrumpHead of firms that pushed 'Italygate' theory falsely claimed VA mansion was her home: report Centrists gain foothold in infrastructure talks; cyber attacks at center of Biden-Putin meeting VA moving to cover gender affirmation surgery through department health care MORE holds a commanding lead over his Republican presidential rivals in his home state of New York but would lose the state in a general election, according to a new poll.

Trump holds a 52-point lead over Ted CruzRafael (Ted) Edward CruzWhite House denies pausing military aid package to Ukraine Ted Cruz says critical race theory is as racist as 'Klansmen in white sheets' Pentagon pulling 'certain forces and capabilities,' including air defenses, from Middle East MORE, 64 to 12 percent, in the Emerson College poll of likely GOP primary voters in New York, which also shows John Kasich at 1 percent.

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But Trump would lose to both Democratic candidates in the state in hypothetical matchups: Hillary ClintonHillary Diane Rodham ClintonWhite House denies pausing military aid package to Ukraine Monica Lewinsky responds to viral HBO intern's mistake: 'It gets better' Virginia governor's race poses crucial test for GOP MORE leads him by 19 points, 55 to 36 percent, and Bernie SandersBernie SandersCentrists gain foothold in infrastructure talks; cyber attacks at center of Biden-Putin meeting Democrats facing tough reelections back bipartisan infrastructure deal The Hill's Morning Report - ObamaCare here to stay MORE leads him by 17 points, 53 to 36 percent.

Cruz, who's running second to Trump in the GOP race, would similarly face unfriendly terrain in New York, losing by 31 points to Clinton, a former senator of the state whose campaign is based in Brooklyn.

Clinton, who was twice elected as a New York senator, locked up wins in five more states on Tuesday, extending her delegate lead. She's favored by 48 points over Sanders, 71 percent to 23 percent, to win the New York primary on April 19, according to the Emerson poll.

The survey of 768 likely general election voters in New York, which traditionally favors Democrats, was conducted March 14–16 via landlines with a margin of error of 3.5 percentage points.

The survey of 298 likely GOP primary voters has a margin of error of 5.6 points, while the survey of 373 likely Democratic primary voters has a margin of error of 5 points.