Florida senator: Trump will win big in state
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"It's obvious," Nelson responded when asked why he thought so, noting recent polling and Trump's overtures in the state.
Trump leads Florida's GOP primary by more than 15 points over Rubio, according to a RealClearPolitics average of polls.
The state's winner-take-all primary March 15 will give 99 delegates to the winner.
Florida is viewed as Rubio's last stand in the GOP race. The senator has won just two contests, in Minnesota and Puerto Rico, and trails Trump and Cruz for delegates.
Rubio, Trump, Cruz and John Kasich are facing off in a GOP presidential debate Thursday night in Miami.
- Updated at 5:49 p.m.