Clinton opens wide leads in Nevada, SC
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New polls show Democratic front-runner Hillary ClintonHillary Diane Rodham ClintonTrump preps conspiracy theory to explain faltering economy The ideological divide on vaping has a clear winner: Smokers Biden struggles to hit it off with millennials MORE opening wide leads in the early voting states of Nevada and South Carolina.

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Fifty percent of likely Democratic caucus-goers in Nevada support Clinton, CNN/ORC International pollsters found. Nevada is host to the first Democratic debate on Tuesday in Las Vegas.

Sen. Bernie SandersBernie SandersTrump preps conspiracy theory to explain faltering economy Sanders doubles down on 'Medicare For All' defense: 'We have not changed one word' Sanders, Warren back major shift to fight drug overdoses MORE (I-Vt.) is 16 points behind Clinton, at 34 percent. Sanders has garnered attention recently for closing in on Clinton in Iowa and surpassing her in New Hampshire.

Vice President Biden takes 12 percent support in Nevada. Biden has come in third in several other state polls as he considers entering the Democratic race.

Clinton has a massive lead in South Carolina, thought to be integral to a potential Biden bid. The former secretary of State is supported by 49 percent of likely primary voters there.

Sanders follows at a distant second, with 24 percent, while Biden takes 18 percent. Former Maryland Gov. Martin O'Malley registers 3 percent support there.

If Biden does not enter the race, Clinton's leads over Sanders would grow to 50 points in South Carolina and 22 points in Nevada.

Democratic voting in Nevada and South Carolina will occur in late February, after Iowa and New Hampshire earlier that month.

The surveys of 301 likely Democratic primary voters in South Carolina and 253 likely Democratic caucus-goers in Nevada were conducted Oct. 3-10 and have margins of error of 5.5 and 6 points, respectively.

— This report was updated at 8:33 a.m.