White House hopeful Marco RubioMarco Antonio RubioWhite House makes push for paid family leave and child care reform Tom Hanks weighs in on primary: 'Anybody can become president' GOP senator blocks bill aimed at preventing Russia election meddling MORE ripped rival Ted CruzRafael (Ted) Edward CruzSenate Republicans air complaints to Trump administration on trade deal Senate passes Armenian genocide resolution Houston police chief stands by criticism of McConnell, Cruz, Cornyn: 'This is not political' MORE at Saturday's presidential debate for a "pattern" of telling lies, particularly about immigration reform.

"This is a disturbing pattern now. For a number of weeks Ted Cruz has just been telling lies," Rubio said. "He's lying about all sorts of things and now he's just making things up." 

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The Florida senator said that Cruz had lied "about Ben Carson in Iowa," referring to the Carson campaign's accusations that Cruz's campaign spread false rumors during the caucuses that the retired neurosurgeon was dropping out of the presidental race. 
 
Rubio's comments came as he and the Texas Republican battled over their stance in a 2013 fight in the Senate over a wide-ranging immigration reform bill. 
  
Cruz has repeatedly knocked Rubio for working with Democrats, calling the "Gang of Eight" bill the "Rubio-Schumer amnesty plan," referring to Sen. Charles SchumerCharles (Chuck) Ellis SchumerSenate confirms Trump's nominee to lead FDA CEO group pushes Trump, Congress on paid family, medical leave Krystal Ball: Is this how Bernie Sanders will break the establishment? MORE (D-N.Y.), who is expected to be the next Democratic leader. 
 
"The question for anyone on illegal immigration, is where were you in that fight," Cruz added. 
 
Rubio, however, has pointed to amendments that the Texas senator pushed that removed a path to citizenship from the bill but kept work permits.
 
Asked about his tactics on the Senate's immigration bill, which ultimately stalled in the House, Cruz has said that the amendments were meant to expose Democrats' "bluff" and ultimately undermine the Gang of Eight bill.
 
Rubio wasn't alone at the South Carolina event in accusing Cruz of lying. Donald TrumpDonald John TrumpSenate gears up for battle over witnesses in impeachment trial Vulnerable Democrats tout legislative wins, not impeachment Trump appears to set personal record for tweets in a day MORE also said Cruz "is the single biggest liar. ...This guy will say anything."