Republican presidential candidate Donald TrumpDonald John TrumpFive challenges awaiting Mattis' successor Meet Trump's pick to take over the Joint Chiefs of Staff Retiring GOP lawmaker blasts Trump's threat to close border as 'angry eighth-grader’s tweet' MORE on Tuesday accused rival Ted CruzRafael (Ted) Edward CruzO'Rourke rips Trump's border wall in video: 'A symbol of division' O'Rourke's chances against Trump are ‘overstated,’ says progressive columnist Bloomberg ready to spend at least 0M if he runs for White House in 2020 MORE of having “a mental problem.”

“Seriously, he’s got a mental problem,” Trump told host Maria Bartiromo on Fox Business Network’s "Mornings with Maria."

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“There’s never been any politician — or almost anybody in my life — that I’ve seen that lies so much.”

Trump said Cruz is misleading Americans about Trump's fundamental policy positions on hot-button topics including gun control and healthcare.

“He will say I’m against the Second Amendment,” he said. “He will say I’m terribly in favor of ObamaCare, which is ridiculous. These are things that are staples of what I'm about.

"I’m totally in favor of the Second Amendment. ... I want the Second Amendment — I’d strengthen it if anything."

Trump added that other GOP White House hopefuls have slammed Cruz for dishonesty.

“By the way, I’m not the only that said it,” he said. "Marco RubioMarco Antonio RubioNauert faces questions about qualifications at UN The Memo: Trump puts isolationism at center stage Trump's military moves accelerate GOP search for next McCain MORE called him a liar during the debate.”

Cruz has repeatedly accused Trump and Rubio of not being sufficiently conservative. He accused both men on Monday of shouting “liar” at critics anytime their actual beliefs are put in the spotlight.

“It is not being honest or candid for either Marco Rubio or Donald Trump to pretend that their records are different than what they are and simply yell and scream at anyone who points to the words that have come out of their own mouths,” Cruz said.