Republican presidential hopeful Jeb Bush on Saturday sneezed at the notion of serving as the running mate to primary front-runner Donald TrumpDonald John TrumpOvernight Health Care: US hits 10,000 coronavirus deaths | Trump touts 'friendly' talk with Biden on response | Trump dismisses report on hospital shortages as 'just wrong' | Cuomo sees possible signs of curve flattening in NY We need to be 'One America,' the polling says — and the politicians should listen Barr tells prosecutors to consider coronavirus risk when determining bail: report MORE.

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“No,” he responded sharply to a reporter in South Carolina, drawing laughs. “Let’s be clear: I don’t think he would ask me.”

Former Republican primary candidate Sen. Lindsey GrahamLindsey Olin GrahamUN biodiversity chief calls for international ban of 'wet markets' Graham asks colleagues to support call for China to close wet markets Justice IG pours fuel on looming fight over FISA court MORE (R-S.C.), who has endorsed Bush for president, can be seen chuckling at the suggestion, as well.

The former Florida governor has repeatedly questioned Trump’s conservatism and balked at the billionaire businessman’s abrasive manner.

Trump, for his part, has needled Bush as a “low-energy” candidate and accused his brother, former President George W. Bush, of lying about the Iraq invasion.