Marco RubioMarco Antonio RubioThe Memo: Saudi storm darkens for Trump GOP leaders hesitant to challenge Trump on Saudi Arabia On The Money: Treasury official charged with leaking info on ex-Trump advisers | Trump to seek 5 percent budget cut from Cabinet members | Mnuchin to decide by Thursday on attending Saudi conference MORE ridiculed Donald TrumpDonald John TrumpThe Guardian slams Trump over comments about assault on reporter Five takeaways from the first North Dakota Senate debate Watchdog org: Tillerson used million in taxpayer funds to fly throughout US MORE's approach to finding Middle East peace, saying that Israeli-Palestinian talks are not like a real estate deal.

"The Palestinians are not a real estate deal, Donald," the White House contender said in Thursday night's CNN Republican debate in Houston.

ADVERTISEMENT

Rubio and Ted CruzRafael (Ted) Edward CruzO'Rourke gives 'a definitive no' to possibility of running in 2020 Vicente Fox endorses Beto O'Rourke in Texas Senate race Beto O'Rourke on impeachment: 'There is enough there to proceed' MORE both hit the billionaire businessman for saying that he would be a neutral broker in peace negotiations between the Israelis and the Palestinians.

Both Rubio and Cruz say they would stand unequivocally with Israel, while the party front-runner argues that neutrality is required to make what would be "probably the toughest deal of any kind."

"A deal is a deal," Trump replied, when Rubio made the point that Middle East peace talks had nothing to do with negotiating real estate.

Rubio hit back: "A deal is not a deal when you're dealing with terrorists. Have you ever negotiated with terrorists?"

Trump, who was under attack from the Florida senator all night, replied, "You are not a negotiator. And with your thinking you will never bring peace."

"Donald might be able to build condos in the Palestinian areas, but ... this is not a real estate deal," Rubio said to close the exchange.