Marco RubioMarco Antonio RubioHillicon Valley: Big Tech hearing the most partisan yet | Rubio warns about foreign election interference | Trump campaign site briefly hacked Rubio warns that election interference may ramp up around Election Day Senate GOP to drop documentary series days before election hitting China, Democrats over coronavirus MORE took aim at Donald TrumpDonald John TrumpHillary Clinton responds to Chrissy Teigen tweet: 'I love you back' Police called after Florida moms refuse to wear face masks at school board meeting about mask policy Supreme Court rejects Trump effort to shorten North Carolina mail-ballot deadline MORE’s manhood during a rally Friday morning, portraying the GOP front-runner as a coward and suggesting he may have wet himself during Thursday night's presidential debate.

"He called me Mr. Meltdown. Let me tell you something, last night during two of the debates, he went backstage, he was having a meltdown," Rubio said in Dallas. 

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"First, he had this little makeup thing applying makeup around his mustache because he had one of those sweat mustaches. Then, he he asked for a full length mirror … maybe to make sure his pants weren’t wet."

The line came as Rubio took out his cellphone and began to read Trump's tweets from stage. Noting that some had misspellings, he cracked that the billionaire businessman "must have hired a foreign worker to do his own tweets."

He chided Trump for trying to portray himself as a "tough guy" and said voters shouldn’t be fooled.

"This is a con-job where he is going to Americans who are struggling, Americans who are hurting, and he’s implying, 'I'm fighting for you' because he’s a tough guy. A tough guy? This guy inherited $200 million, he’s never faced any struggle," Rubio said. 

“The other day, he told somebody, a protestor, 'I'm going to punch you in the face.' Donald Trump has never punched anyone else in the face. Donald Trump was the first guy to beg for Secret Service protection.” 

The attacks come the morning after a surprisingly contentious debate, hosted in Houston by CNN, that largely pitted the Florida senator against Trump in a series of attacks. The GOP race pivots to Super Tuesday in just days, when one-quarter of the race's total GOP delegates are up for grabs.