Democratic presidential hopeful Bernie SandersBernie SandersSunday shows preview: All eyes on Biden administration to tackle coronavirus The Hill's 12:30 Report: Next steps in the Trump impeachment Sanders selling sweatshirts with his famous inauguration pose for charity MORE won't run as an independent, his wife Jane Sanders said Tuesday, dismissing advice from Republican front-runner Donald TrumpDonald TrumpNYT: Rep. Perry played role in alleged Trump plan to oust acting AG Arizona GOP censures top state Republicans McCain, Flake and Ducey Biden and UK prime minister discuss NATO, multilateralism during call MORE.

"I think we've been very clear right from the beginning that we will not play the role of spoiler," Jane Sanders said on CNN's "Wolf." "Bernie will not be running as an independent."

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Trump earlier Tuesday tweeted that Bernie Sanders "has been treated terribly by the Democrats" in the campaign.

"He should show them, and run as an Independent!" Trump wrote of the Independent senator from Vermont.

Trump himself has repeatedly flirted with an independent bid, warning the GOP to treat him fairly during the primary process. The GOP front-runner appears focused now on fending off a challenge from rivals Ted CruzRafael (Ted) Edward CruzBiden leans on Obama-era appointees on climate Ethics complaint filed against Biggs, Cawthorn and Gosar over Capitol riot Hawley, Cruz see approval ratings dip in wake of Capitol riot: poll MORE and John Kasich, who are coordinating to deny him enough delegates to force a contested Republican National Convention in July.

Asked if she thought Democrats had treated her husband fairly, Jane Sanders said, "Yes, but the process needs to change. We need an open electoral system."

The Sanders campaign has criticized states with closed primaries, arguing they prevented independent voters from showing their support.

Jane Sanders also said that her husband didn't want to splinter Democrats in the November general election.

"We cannot afford a Republican in the White House. We cannot afford a Republican appointing Supreme Court justices," she said.

She insisted that Sanders' "political revolution ... will be a force to be reckoned with" regardless of whether he wins the Democratic nomination.

Bernie Sanders has said any other nominee will need to win over his supporters, giving him leverage.

Hillary ClintonHillary Diane Rodham ClintonBiden must wait weekend for State Department pick Texas Supreme Court rejects Alex Jones request to toss lawsuits from Sandy Hook parents Paris Agreement: Biden's chance to restore international standing MORE, the Democratic front-runner, is favored in polls in several Northeastern states voting Tuesday. She expanded her delegate lead over Sanders by winning New York last week.