Fresh off his victory in Indiana, Democratic presidential candidate Bernie SandersBernard (Bernie) SandersThe Memo: Tide turns on Kavanaugh Election Countdown: Trump confident about midterms in Hill.TV interview | Kavanaugh controversy tests candidates | Sanders, Warren ponder if both can run | Super PACs spending big | Two states open general election voting Friday | Latest Senate polls READ: President Trump’s exclusive interview with Hill.TV MORE expressed confidence that he can pull off "one of the great political upsets" in American history to defeat Democratic front-runner Hillary ClintonHillary Diane Rodham ClintonHillicon Valley: Trump's exclusive interview with Hill.TV | Trump, intel officials clash over Russia docs | EU investigating Amazon | Military gets new cyber authority | Flynn sentencing sparks new questions about Mueller probe READ: President Trump’s exclusive interview with Hill.TV Keeping up with Michael Avenatti MORE and presumptive GOP nominee Donald Trump.

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At a Tuesday night press conference, the Vermont senator touted the momentum of his campaign while acknowledging that it's an uphill battle for him to clinch the nomination.

"We feel great about tonight, not only in winning here in Indiana ... but also gaining the momentum we need to take us to the finish line," Sanders said. "I sense some great deal of momentum.

"I sense some great victories coming, and I think while the path is narrow — and I do not deny that for a moment — I think we can pull off one of the great political upsets in the history of the United States and, in fact, become the nominee for the Democratic Party," he continued. "And once we secure that position, I have absolute confidence that we are gonna defeat Donald Trump in the general election."

The Indiana Democratic primary was too close to call once all the polls closed at 7 p.m. EDT. The contest was neck and neck, but Sanders later pulled ahead of Clinton.

As of 11 p.m., Sanders led 52 percent to 48 percent, with 95 percent of precincts reporting, according to The Associated Press.

Sanders said he believes he's the best candidate to take on Trump in November. The real estate mogul is now the presumptive GOP nominee after his landslide victory in Indiana prompted Texas Sen. Ted CruzRafael (Ted) Edward CruzSinger Leon Bridges to join Willie Nelson in performing at O’Rourke rally Election Countdown: Trump confident about midterms in Hill.TV interview | Kavanaugh controversy tests candidates | Sanders, Warren ponder if both can run | Super PACs spending big | Two states open general election voting Friday | Latest Senate polls Poll: Beto O'Rourke leads Cruz by 2 points in Texas Senate race MORE to suspend his campaign.

The Vermont senator’s victory in the Hoosier State breaks Clinton's recent winning streak. But though he won Indiana, the state's Democratic primary allocates delegates proportionally, so he will barely make a dent in the former secretary of State's delegate lead.

Clinton is shy of the Democratic nomination by 182 delegates, according to the AP delegate tracker. Sanders would need to win every remaining pledged delegate and sway more superdelegates to his side to reach that threshold.

On Tuesday night, Sanders said he will continue to "make the case" to the superdelegates that reside in states where he claimed resounding victories.

"I believe we’ll be able to make the case to many of those superdelegates that what is most important is not whether Hillary Clinton or Bernie Sanders is the nominee," Sanders said. "What is most important is that we do not allow someone like a Donald Trump to become president of the United States."