GOP senators: We could work with Hillary Clinton
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Sen. Johnny IsaksonJohnny IsaksonCritical race theory becomes focus of midterms Former Georgia ethics official to challenge McBath Loeffler meets with McConnell amid speculation of another Senate run MORE (R-Ga.) is predicting that congressional Republicans will be more willing to work with Hillary ClintonHillary Diane Rodham ClintonDemocrats worry negative images are defining White House Heller won't say if Biden won election Whitmer trailing GOP challenger by 6 points in Michigan governor race: poll MORE than they have been with President ObamaBarack Hussein ObamaTop nuclear policy appointee removed from Pentagon post: report Prosecutors face legal challenges over obstruction charge in Capitol riot cases Biden makes early gains eroding Trump's environmental legacy MORE, should she be elected president.  

"Barack Obama was somewhat of an unknown – he was a senator, but only for a year-and-a-half before he was elected president. She is a known commodity, and I think there’ll be more camaraderie in terms of working together, than there might have been in the early days of Obama," Isakson told the Atlanta Journal Constitution. 
Democrats have repeatedly blasted Republican tactics under the Obama administration, arguing that GOP senators have reached a record level of obstruction on legislation and nominations. 
Retiring Senate Minority Leader Harry ReidHarry Mason ReidTo Build Back Better, we need a tax system where everyone pays their fair share Democrats say Biden must get more involved in budget fight Biden looks to climate to sell economic agenda MORE (D-Nev.) took a final pre-election swing at Republicans from the Senate floor last month, saying lawmakers had treated Obama with "unprecedented disrespect." 
Isakson's comments come as Clinton has narrowly trailed Trump in the typically red state, feeding Democrats hopes of expanding the electoral map. According a RealClearPolitics average of polls, the GOP presidential nominee is leading by less than 5 points. 
The Georgia Republican isn't the only one who is open to collaborating with a hypothetical Clinton administration, even though multiple congressional committees are still probing her time atop the State Department. 
"I can do two things at once. I can criticize and I can cooperate," he told The Hill last month. "I don't see that they're inconsistent." 
Sen. John CornynJohn CornynSenate panel advances antitrust bill that eyes Google, Facebook Democrats up ante in risky debt ceiling fight Senate parliamentarian nixes Democrats' immigration plan MORE (R-Texas)—while stressing that he doesn't believe Clinton will win in November—said Americans expect GOP senators to work with whoever is in the White House. 
"We'll do our duty, you know regardless of who is president," the Senate's No. 2 Republican told The Hill last week. "The people we serve want us to to work together for their benefit so that's certainly my posture." 
Cornyn declined to name specific issues that he believes he and Clinton could work well together on. 
Republicans are defending 24 Senate seats in November, including a handful in purple states previously carried by President Obama. They will lose control of the Senate if Democrats net five Senate seats, or four if Clinton also wins the White House.