Sen. Amy KlobucharAmy KlobucharKlobuchar confident spending bill will be finished before Christmas Sunday shows preview: New COVID-19 variant emerges; supply chain issues and inflation persist The Hill's 12:30 Report: Biden renominates Powell as Fed chair MORE (D-Minn.) is the most popular senator running for reelection, while Joe Lieberman (I-Conn.) is the least, according to new polling data.

Public Policy Polling (PPP), a Democratic-leaning firm, looked at the approval ratings for 59 senators during the second half of 2010, and several of them will face voters in 2012. The senators were ranked by the spread between their approval numbers and disapproval numbers.

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Of the 59, Klobuchar is the most popular, with an approval rating of 59 and a disapproval of 29 (a 30-point spread), while Lieberman has an approval rating of 33 and a disapproval of 54 (a 21-point spread).

Lieberman hasn't said what he'll do in 2012, but Klobuchar is preparing for rivals, including a possible challenge from Tea Party darling Rep. Michele BachmannMichele Marie BachmannBoehner says he voted for Trump, didn't push back on election claims because he's retired Boehner: Trump 'stepped all over their loyalty' by lying to followers Boehner finally calls it as he sees it MORE (R-Minn.).

Coming in second was Sen. Scott Brown (R-Mass.), who's also up in 2012. He had a 53 percent approval and 29 percent disapproval (a 24-point spread). Sen. Judd Gregg (R-N.H.), who is retiring, was third, and Sen. Olympia Snowe (R-Maine), also up in 2012, was fourth, with a 56 percent approval and 34 percent disapproval (a 22-point spread).

Of other senators up in 2012, near the bottom were Sens. Claire McCaskillClaire Conner McCaskillLobbying world Ex-Rep. Akin dies at 74 Republicans may regret restricting reproductive rights MORE (D-Mo.) — 43 approval/44 disapproval; Bob CaseyRobert (Bob) Patrick CaseySenators urging federal investigation into Liberty University's handling of sexual assault claims Crucial talks on Biden agenda enter homestretch Senate Democrats call for diversity among new Federal Reserve Bank presidents MORE Jr. (D-Pa.) — 36 approval/40 disapproval; and John Ensign (R-Nev.) — 41 approval/48 disapproval.
   
Retiring Sen. Roland Burris (D-Ill.) came in last, with a 19 percent approval rating and a 58 percent disapproval rating.

PPP's Tom Jensen notes in his analysis that "the average approval rating for a senator right now is 43 percent approving to 40 percent disapproving" and that "there's very little difference in the average approval of Republican senators versus Democratic senators." The average GOP senator had a 43/37 split, while the average Democrat rated a 44/41. 

Several senators up for reelection came in under the 50 percent approval mark, including: Sens. Ben CardinBenjamin (Ben) Louis CardinIt's time for Congress to guarantee Medigap Health Insurance for vulnerable Americans with kidney disease Senators call for Smithsonian Latino, women's museums to be built on National Mall Democrats plow ahead as Manchin yo-yos MORE (D-Md.), Kay Bailey Hutchison (R-Texas), Tom CarperThomas (Tom) Richard CarperFive ways Senate could change Biden's spending plan Advocates see pilot program to address inequalities from highways as crucial first step Democrats plow ahead as Manchin yo-yos MORE (D-Del.), Jon Kyl (R-Ariz.), Jim Webb (D-Va.), Kirsten GillibrandKirsten GillibrandKlobuchar confident spending bill will be finished before Christmas Five ways Senate could change Biden's spending plan This Thanksgiving, skip the political food fights and talk UFOs instead MORE (D-N.Y.), Sherrod BrownSherrod Campbell BrownBiden faces new pressure from climate groups after Powell pick Five Senate Democrats reportedly opposed to Biden banking nominee Senate Democrats call on Biden to push for COVID-19 vaccine patent waivers at WTO MORE (D-Ohio), Bill NelsonClarence (Bill) William NelsonThis Thanksgiving, skip the political food fights and talk UFOs instead Two trajectories to Mars by the 2030s Russian weapons test endangers the International Space Station MORE (D-Fla.), Maria CantwellMaria Elaine CantwellScott says he will block nominees until Biden officials testify on supply chain crisis Airlines staff up for holiday onslaught Manchin set to make or break Biden's climate pledge MORE (D-Wash.) and Debbie StabenowDeborah (Debbie) Ann StabenowFive ways Senate could change Biden's spending plan Senate Democrats look to fix ugly polling numbers Ford announces plans to increase electric vehicle production to 600K by 2023 MORE (D-Mich.).