Republicans have clinched Senate control in an election night that saw Democrats around the country crushed by the growing unpopularity of President Obama.

Democratic losses piled up throughout the night, with the GOP securing a Senate majority before midnight as Sen. Kay HaganKay Ruthven HaganTillis trails Democratic challenger by 7 points in North Carolina poll North Carolina businessman will challenge Tillis in GOP primary Embattled senators fill coffers ahead of 2020 MORE lost in North Carolina and Republican Joni Ernst won an open seat in Iowa.

Incumbent Democrats also fell in House and gubernatorial races, adding to the scale of the party's defeat. High-profile Democratic targets including Wisconsin Gov. Scott Walker (R) prevailed, and the party failed to pick up a single Senate seat. 

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The GOP needed to gain six seats to win the majority, and had already gained seven seats before polls even closed in Alaska. There, Republican Dan Sullivan has opened a lead over Sen. Mark BegichMark Peter BegichAlaska political mess has legislators divided over meeting place Former GOP chairman Royce joins lobbying shop Lobbying world MORE (D) with nearly all of the vote counted. 

Republicans won open seats held by Democrats in Montana, West Virginia, Iowa and South Dakota, and knocked off incumbents in North Carolina, Arkansas and Colorado.

Their majority could grow larger — Sen. Mary LandrieuMary Loretta LandrieuCongress needs to work to combat the poverty, abuse and neglect issues that children face Dems wrestle over how to vote on ‘Green New Deal’ Lobbying world MORE (D-La.) will be the underdog in a runoff election in December against Republican Rep. Bill Cassidy. Sen. Mark WarnerMark Robert WarnerHillicon Valley: Zuckerberg courts critics on Capitol Hill | Amazon makes climate pledge | Senate panel approves 0M for state election security Zuckerberg woos Washington critics during visit Zuckerberg to meet with lawmakers to discuss 'future internet regulation' MORE (D-Va.) was also clinging to a razor-thin lead in Virginia that appeared headed for a recount.

If both Sullivan and Cassidy eventually prevail, that margin could grow to nine seats netted by the GOP by the end of the cycle. 

Sen. Mitch McConnellAddison (Mitch) Mitchell McConnellPatagonia says to shut stores for a few hours during Global Climate Strike Overnight Health Care — Presented by Partnership for America's Health Care Future — Pelosi unveils signature plan to lower drug prices | Trump says it's 'great to see' plan | Progressives pushing for changes On The Money: House votes to avert shutdown, fund government through November | Judge blocks California law requiring Trump tax returns | Senate panel approves three spending bills MORE (R-Ky.) easily won his reelection fight, and the other wins ensure he will fulfill his long-held dream of becoming Senate majority leader.

McConnell was declared the victor in his closely watched race as soon as polls closed in the Bluegrass State, defeating Democrat Alison Lundergan Grimes to earn a sixth term. Democrats had early hopes for the Kentucky secretary of State's candidacy, but her campaign couldn't take advantage of the senator's unpopularity in the state. 

McConnell had to wait for several more hours to learn which way Senate control would fall. But the GOP leader's counterpart admitted just before midnight that Democrats had been ushered from power. 

"I'd like to congratulate Senator McConnell, who will be the new Senate Majority Leader. The message from voters is clear: they want us to work together. I look forward to working with Senator McConnell to get things done for the middle class," said now-Senate Majority Leader Harry ReidHarry Mason ReidBarr fails to persuade Cruz on expanded background checks Harry Reid warns Trump 'can be reelected' Homeland Security Republican accuses Navy of withholding UFO info MORE (D-Nev.). 

The change in power means that Obama will spend the last two years of his presidency dealing with an emboldened all-Republican Congress that intends to challenge him on major legislation and, in the words of McConnell, take the country in a “new direction.”

Hagan's loss to state Speaker Thom Tillis was one of the most surprising results of the night, and her fall sealed the Democratic Party's 2014 fate.

Arkansas Sen. Mark PryorMark Lunsford PryorMedicaid rollback looms for GOP senators in 2020 Cotton pitches anti-Democrat message to SC delegation Ex-Sen. Kay Hagan joins lobby firm MORE (D) was the first incumbent to fall on Tuesday. Freshman Rep. Tom CottonThomas (Tom) Bryant CottonZuckerberg woos Washington critics during visit Zuckerberg to meet with lawmakers to discuss 'future internet regulation' 2020 Democrats raise alarm about China's intellectual property theft MORE (R) handily defeated the centrist lawmaker in a state that has slipped rapidly away from Democrats in recent years.

Colorado Rep. Cory GardnerCory Scott Gardner The 13 Republicans needed to pass gun-control legislation Bolton returns to political group after exiting administration The Hill's Morning Report — Trump's hurricane forecast controversy won't go away MORE (R) knocked off Sen. Mark UdallMark Emery UdallPoll: Trump trails three Democrats by 10 points in Colorado The Hill's Morning Report — Trump and the new Israel-'squad' controversy Colorado candidates vying to take on Gardner warn Hickenlooper they won't back down MORE (D), defying Democratic cries that their vaunted ground game would save the vulnerable incumbent. 

Republicans also picked up a Democrat-held open seat in West Virginia with Rep. Shelley Moore CapitoShelley Wellons Moore CapitoThis week: House jump-starts effort to prevent shutdown Congress set to ignore Trump's wall request in stopgap measure America is in desperate need of infrastructure investment: Senate highway bill a step in the right direction MORE's (R) easy victory. 

South Dakota flipped to the GOP column after former Gov. Mike Rounds (R) won the open seat of retiring Democratic Sen. Tim JohnsonTimothy (Tim) Peter JohnsonTrump faces tough path to Fannie Mae, Freddie Mac overhaul Several hurt when truck runs into minimum wage protesters in Michigan Senate GOP rejects Trump’s call to go big on gun legislation MORE (D). The three-way race had become a late headache for the GOP with the addition of former GOP Sen. Larry Pressler (I), but with Republican attention and help the race turned again in Republicans' favor. 

Rep. Steve Daines (R) then won the open Democratic-held seat in Montana. 

Republican leaders crowed over the victory, arguing voters had sent a strong signal about which party they want in control in Washington.

"The American people have put their trust in the Republican Party, sending a GOP majority to the U.S. Senate. I want to congratulate all our candidates tonight," Republican National Committee Chairman Reince Priebus said in a statement. "Our party's principles and message resonated with voters across the country. This was a rejection of President Obama's failed polices and Harry Reid's dysfunctional Senate."

This post was updated at 5:02 a.m. on November 5.