On the heels of Sen. Mary LandrieuMary Loretta LandrieuCassidy wins reelection in Louisiana Bottom line A decade of making a difference: Senate Caucus on Foster Youth MORE's (D-La.) crushing loss in Louisiana Senate, Republicans were quick to tie her defeat to the Democratic Party's heir apparant: Hillary ClintonHillary Diane Rodham ClintonCruz: Wife 'pretty pissed' about leaked Cancun texts CBC would back Young for OMB if Tanden falls Hillary Clinton to co-write political thriller MORE

Republican National Committee chairman Reince Priebus crowed that Louisianans had “rejected the Democrat agenda and the Obama-Clinton policies that have produced higher healthcare costs and job-killing regulations.”

Sen. Rand PaulRandal (Rand) Howard PaulSanders votes against Biden USDA nominee Vilsack Senate confirms Vilsack as Agriculture secretary Hillicon Valley: Biden to take 'executive action' to address SolarWinds breach | Facebook and Google respond to Australian proposed law | DOJ charges North Korean hackers with stealing .3 billion in cryptocurrency MORE (R-Ky.), a likely Republican presidential contender in 2016, also sought to hang the loss around Clinton, the frontrunner for the Democratic nominatio. 

The RNC said its new majority would allow it to pass the “pro-jobs legislation that was stalled in the Senate when Democrats were in control.”

“Bill Cassidy will be a champion for policies that create jobs and grow the economy, especially building the Keystone Pipeline,” Priebus said in a statement. “And as a doctor treating the uninsured, he has seen firsthand how ObamaCare has hurt healthcare in this country and will work toward market-driven, patient-centered reforms. Americans’ priorities will be Republicans’ priorities in the new Senate.”