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The Tea Party-affiliated group is airing two weeks of radio ads attacking the senator in Atlanta, making him their fourth target, alongside Sens. Lindsey GrahamLindsey Olin GrahamThe Memo: Trump and McCabe go to war Graham seeks new Rosenstein testimony after explosive McCabe interview Senate confirms Trump pick William Barr as new attorney general MORE (R-S.C.), Lamar AlexanderAndrew (Lamar) Lamar AlexanderCongress must move forward on measure dealing with fentanyl GOP advances rules change to speed up confirmation of Trump nominees Key doctors group faces political risks on guns MORE (R-Tenn.) and Richard BurrRichard Mauze BurrThe Hill's 12:30 Report — Presented by Kidney Care Partners — Lawmakers scramble as shutdown deadline nears Drama hits Senate Intel panel’s Russia inquiry Cohen to testify before three congressional panels before going to prison MORE (R-N.C.). Like Burr, Isakson isn't up for reelection until 2016.

"Republicans in Congress can stop ObamaCare by refusing to fund it, but Sen. Johnny IsaksonJohn (Johnny) Hardy IsaksonOn The Money: Lawmakers wait for Trump verdict on border deal | Trump touts deal as offering B for security | McConnell presses Trump to sign off | National debt tops T | Watchdog details IRS shutdown woes Trump criticizes border wall deal: 'Can't say I'm happy' GOP senators offer praise for Klobuchar: 'She’s the whole package' MORE refuses to join the fight," the ad intones. "Johnny Isakson voted to give President Obama money to implement ObamaCare earlier this year, and he'll do it again if you don't make your voice heard."

The ad is part of a broader campaign to push Republicans to back Sen. Mike LeeMichael (Mike) Shumway LeeSenate approves border bill that prevents shutdown Push for paid family leave heats up ahead of 2020 New act can help us grapple with portion of exploding national debt MORE's (R-Utah) campaign to use the impending debate over funding the government to try to force Democrats to defund ObamaCare. So far, 14 GOP senators have signed on, but a number of others have disagreed with the plan.