A former adviser to President Barack ObamaBarack Hussein ObamaAs Democrats gear up to challenge Trump in 2020, the key political divide will be metropolitan versus rural Trump's take on midterms: ‘Epic' win in Senate, ‘better than other sitting Presidents’ in House NASA's carpool to Space Station is back on as Russian rocket Soyuz quickly returns to flight MORE on Wednesday cautioned against talk that President Trump is unfit for office, saying it opens the door to a potentially “dangerous road.” 

“The inference was that somehow there should be some effort to remove him, or at least that’s how some people would have heard it,” David Axelrod told CNN’s “The Situation Room.”

“And I think we have to be very, very careful when we have these discussions because we have a system, a Constitutional system.” 

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Axelrod specifically referenced comments made by former Director of National Intelligence James Clapper, who said he questions Trump’s fitness for the presidency following his remarks at a Tuesday night rally in Phoenix. 

"I really question ... his fitness to be in this office," Clapper said late Tuesday.

"I also am beginning to wonder about his motivation for it, maybe he is looking for a way out." 

Axelrod said while he took Clapper’s remarks seriously, they made him “nervous.”

“And if people get a sense that there’s some extraordinary measure that’s going to be taken to effect what they would view as a bloodless coup,” Axelrod explained. 

“Remember a third of the country supports this president, that’s a very dangerous road to go down. And if you ever did go down that road, you’re open a Pandora’s box that will never end.”