In the wake of his losing the chairmanship of the Republican National Committee to Reince Priebus, Saul Anuzis said Saturday that he is considering a run against Sen. Debbie Stabenow (D-Mich) in 2012.

“I haven’t ruled anything out,” Anuzis said in an appearance on local WWJ-TV's “Michigan Matters” broadcast Saturday.

Anuzis also lost out to Michael Steele in a run to be RNC chairman in 2009.

“Reince was a safe choice. He was a good chairman and good fundraiser. Wisconsin had a great year,” he said of the RNC contest.

Anuzis, former chairman of Michigan’s Republican Party, may face former Gov. John Engler, the former head of the National Association of Manufacturers, or former Rep. Pete Hoekstra (R-Mich.) or Rep. Mike Rogers (R-Mich.) in a primary contest.

Stabenow is seen as especially vulnerable in a state that has borne the brunt of the recession in terms of unemployment. A Detroit News/WDIV-TV poll out Jan. 6 found that only 37 percent approve of Stabenow's job performance. Stabenow serves as the chairwoman of the Senate Agriculture Committee and may find crafting the 2012 Farm Bill and battling for re-election a tall order.