Centrist Sen. Olympia Snowe (R-Maine) said Tuesday that she will vote against Rep. Paul RyanPaul Davis RyanBudowsky: Why I back Kennedy, praise Markey Democratic super PAC quotes Reagan in anti-Trump ad set to air on Fox News: 'Are you better off?' Trump lashes out at Reagan Foundation after fundraising request MORE's (R-Wis.) budget when it comes up for a vote in the Senate.

Snowe, who is up for reelection in 2012, praised Ryan for proposing a budget but said that she disagrees with the way it reforms Medicare.

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"I am going to vote 'no' on the budget because I have deep and abiding concerns about the approach on Medicare, which is essentially to privatize it," Snowe told The Portland Press Herald.

Snowe joins her fellow Maine Sen. Susan CollinsSusan Margaret CollinsThe Hill's Campaign Report: Trump's visit to battleground Ohio overshadowed by coronavirus New polls show tight races for Graham, McConnell McConnell goes hands-off on coronavirus relief bill MORE (R) and Massachusetts Sen. Scott Brown (R), each a centrist who has said they will oppose the budget. Like Snowe, Brown faces reelection in 2012. 

Freshman Sen. Rand PaulRandal (Rand) Howard PaulTrump-backed Hagerty wins Tennessee GOP Senate primary Senators introduce bill to block Trump armed drone sale measure The Hill's Campaign Report: Trump's visit to battleground Ohio overshadowed by coronavirus MORE (R-Ky.) has also said he will vote against it, but he says that's because the plan does not go far enough in cutting spending.

Senate Majority Leader Harry ReidHarry Mason ReidMcConnell goes hands-off on coronavirus relief bill Kamala Harris to young Black women at conference: 'I want you to be ambitious' Obama calls filibuster 'Jim Crow relic,' backs new Voting Rights Act bill MORE (D-Nev.) is expected to hold a vote soon, possibly this week, on the plan. The plan is expected to fail, but Reid has said it could elucidate divisions within the Republican Party.

Democrats have seized on Ryan's Medicare plan, criticizing it as an extreme proposal that would privatize the popular, but fiscally troubled, entitlement program. Recently, they have dubbed it the GOP's "litmus test," playing up incidents in which Republicans have split with the plan.

All but four House Republicans voted for Ryan's budget.

Snowe's position is not surprising. She has not praised the Medicare reforms proposed by Ryan, the chairman of the House Budget Committee.

But she also criticized Reid for holding the vote on the Ryan budget, saying it won't foster a true budget debate.

"[Ryan] is not going to have all the answers or the answers that I am going to agree with, but the question is, can we work to improve it, to modify it? But we don't even have the opportunity in the Senate," Snowe said. "That's what we're facing, an up-or-down vote, all or nothing, and it doesn't need to be that way."