Sen. Lindsey GrahamLindsey Olin GrahamSenate GOP aims to confirm Trump court pick by Oct. 29: report The Hill's Campaign Report: GOP set to ask SCOTUS to limit mail-in voting Senate GOP sees early Supreme Court vote as political booster shot MORE (R-S.C.) on Thursday called on Republican presidential candidates Donald TrumpDonald John TrumpOmar fires back at Trump over rally remarks: 'This is my country' Pelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Trump mocks Biden appearance, mask use ahead of first debate MORE and Ted CruzRafael (Ted) Edward CruzTrump argues full Supreme Court needed to settle potential election disputes Press: Notorious RBG vs Notorious GOP The Hill's Morning Report - Sponsored by Facebook - Washington on edge amid SCOTUS vacancy MORE to stop feuding over Cruz's wife.
 
"It's a good year to be single," Graham quipped during an interview on NBC's "Today" show.
 
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"The bottom line is, when you think it can't get worse ... hey guys, knock it off. The world is falling apart. Man up. You've got great wives and great families," Graham said.
 
Graham said the candidates should instead focus on the battle against the Islamic State in Iraq and Syria (ISIS) in the wake of the deadly terrorist attacks in Brussels this week. 
 
"Talk about things people really care about and knock this crap off, because these are serious times and you're not behaving like you want to be president of the United States, you're behaving like you're on a reality TV show," Graham added.
 
Late Wednesday night, Trump doubled down on his attack of Cruz's wife Heidi, sharing a tweet comparing her with his wife Melania, a former model, and stating, "A picture is worth a thousand words."
 
It came on the heels of his threat earlier this week to "spill the beans" about Heidi Cruz in the wake of an ad from an anti-Trump group that featured a nude photo of Melania from a magazine photoshoot.
 
Trump claimed the ad was from Cruz, though has not produced any evidence to support that. Cruz has denied any involvement with the group and blasted Trump, saying that "real men don't attack women."
 
"Your wife is lovely, and Heidi is the love of my life," Cruz said in a tweet responding to the attack.