Nancy-Ann DeParle, a White House deputy chief of staff and the president's point person on his signature health care law, is leaving the West Wing to join the Brookings Institution. 

Brookings president Strobe Talbott announced in a post on Twitter that the longtime Obama staffer would work as a guest scholar for the think tank.

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Before being named deputy chief of staff, DeParle served as the director of the White House Office of Health Reform. In that role, she led the administration's efforts on health care issues during the contentious debate over the Affordable Care Act.

Before joining the Obama administration, DeParle served as a key health policy adviser to President Clinton, and ran the Medicare, Medicaid, and SCHIP programs during his tenure. She previously work as associate director for health and personnel at the Office of Management and Budget, and served as a fellow at Harvard's Kennedy School and an adjunct professor at the University of Pennsylvania's Wharton School during the Bush Administration.

DeParle's exit comes at a time when the Obama administration is being criticized for a string of white, male appointments to high-level positions. On Wednesday, the White House posted a picture to its social media networks featuring DeParle, among other female staffers, as an apparent rebuttal to a New York Times report commenting on the "all-male look" of the president's inner circle.

It also comes just a day after her boss, White House chief of staff Jack LewJacob (Jack) Joseph LewThe Hill's Morning Report - Biden argues for legislative patience, urgent action amid crisis On The Money: Senate confirms Yellen as first female Treasury secretary | Biden says he's open to tighter income limits for stimulus checks | Administration will look to expedite getting Tubman on bill Sorry Mr. Jackson, Tubman on the is real MORE, was nominated to head the Treasury Department. DeParle had been considered a contender to replace Lew, although recent reports suggest that the president has narrowed his search to deputy national security adviser Denis McDonoughDenis Richard McDonoughExpats plead with US to deliver COVID-19 vaccines Veteran suicides dropped to lowest level in 12 years Veterans grapple with new Afghanistan: 'Was my service worth it?' MORE and Ron Klain, the former chief of staff to vice presidents Joe BidenJoe BidenJan. 6 panel lays out criminal contempt case against Bannon Overnight Energy & Environment — Presented by the American Petroleum Institute — Democrats address reports that clean energy program will be axed Two House Democrats to retire ahead of challenging midterms MORE and Al GoreAlbert (Al) Arnold GoreMcAuliffe on 2000 election: 'I wish the United States Supreme Court had let them finish counting the votes' All Democrats must compromise to pass economic plans, just like 1993 Amy Coney Barrett sullies the Supreme Court MORE.