Former Democratic presidential candidate Sen. Bernie SandersBernie SandersBriahna Joy Gray: Push toward major social spending amid pandemic was 'short-lived' Sanders 'disappointed' in House panel's vote on drug prices Manchin keeps Washington guessing on what he wants MORE (I-Vt.) on Friday released an Inauguration Day message urging supporters to “fight back” against Donald TrumpDonald TrumpOhio Republican who voted to impeach Trump says he won't seek reelection Youngkin breaks with Trump on whether Democrats will cheat in the Virginia governor's race Trump endorses challenger in Michigan AG race MORE's agenda.

“Today is going to be a tough day for millions of Americans, including myself,” Sanders said in a video posted on Twitter. “But our response has got to be not to throw up our hands in despair — not to give up — but in fact to fight back as effectively and as vigorously as we can.

“And our job is to keep our eyes on the prize, and the prize is that we will continue fighting for a government that represents all of us; not just the 1 percent,” he continued. “And we are going to go forward, in the fight for economic, social, environmental and racial justice. That’s who we are, that’s what we are going to do. We are not giving up.”

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Sanders’s comments were posted just hours before Trump was set to take the Oath of Office.

The Vermont senator gained a sizable following among progressive Democrats during the 2016 primaries with his critique of economic and social inequality in the U.S., but eventually lost the primaries to Hillary ClintonHillary Diane Rodham ClintonAttorney indicted on charge of lying to FBI as part of Durham investigation Durham seeking indictment of lawyer with ties to Democrats: reports Paul Ryan researched narcissistic personality disorder after Trump win: book MORE.

Sanders has said in recent weeks that he sees opportunities to work with Trump, particularly on job creation and a plan to overhaul the nation’s crumbling infrastructure. Still, he has not shied away from criticizing the president-elect, and has vowed to oppose him on a number of issues, such as climate change, which Trump has called a “hoax.”'

Some protesters took to the streets of Washington ahead of Trump's inauguration. Bigger protests are expected on Saturday.