Democratic National Committee (DNC) Chairman Tom PerezThomas Edward PerezClinton’s top five vice presidential picks Government social programs: Triumph of hope over evidence Labor’s 'wasteful spending and mismanagement” at Workers’ Comp MORE on Wednesday said "time will tell" if Alexandria Ocasio-Cortez's (D) primary victory over Rep. Joe CrowleyJoseph (Joe) CrowleyDemocrats work to bring labor on board trade deal The Democrats' generational battle Ocasio-Cortez apologizes for blocking ex-politician on Twitter, settles lawsuit MORE (D-N.Y.) signals the party's base is eager for new leadership.

In an interview with MSNBC's Hallie Jackson, the DNC chief also declined to call for older Democratic leaders such as Senate Minority Leader Charles SchumerCharles (Chuck) Ellis SchumerKrystal Ball: Is this how Bernie Sanders will break the establishment? TikTok chief cancels Capitol Hill meetings, inflaming tensions Overnight Health Care — Presented by That's Medicaid — Deal on surprise medical bills faces obstacles | House GOP unveils rival drug pricing measure ahead of Pelosi vote | Justices to hear case over billions in ObamaCare payments MORE (N.Y.) and House Minority Leader Nancy PelosiNancy PelosiThe Hill's Morning Report - Sponsored by AdvaMed - House panel expected to approve impeachment articles Thursday Democrats seek leverage for trial The Memo: Pelosi-Trump trade deal provokes debate on left MORE (Calif.) to step aside in favor of younger lawmakers.

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"I'm wondering if this victory by Ocasio-Cortez signals to you a frustration with where Democratic leadership is right now, whether this is a sign coming from progressives, coming from some Democrats that Nancy Pelosi and Chuck SchumerCharles (Chuck) Ellis SchumerKrystal Ball: Is this how Bernie Sanders will break the establishment? TikTok chief cancels Capitol Hill meetings, inflaming tensions Overnight Health Care — Presented by That's Medicaid — Deal on surprise medical bills faces obstacles | House GOP unveils rival drug pricing measure ahead of Pelosi vote | Justices to hear case over billions in ObamaCare payments MORE need to step aside and let in some new blood?" Jackson asked Perez.

"Time will tell, but I think what we've seen in elections across the country are candidates who won by focusing on the issues that were keeping their constituents up at night," he responded.

Ocasio-Cortez scored an upset victory over Crowley, the no. 4 House Democrat, in Tuesday's primary, winning 58 percent of the vote to Crowley's 42 percent.

When asked who he would support to lead Democrats in Congress if Pelosi or Schumer were to step aside, Perez said: "I'll leave that to other people."

Pelosi has vowed to run for House speaker again if the Democrats regain control of the chamber.

Perez was also asked if Pelosi is the right person to lead the party going forward.

"That is up for the Democratic leadership to decide," Perez said. "I have great respect for Nancy Pelosi. She has done great work for the Affordable Care Act, it exists because of Nancy Pelosi."

Pelosi has faced criticism from some House Democrats who say there's a lack of a cohesive agenda for the caucus. New York Rep. Brian HigginsBrian Higgins'Medicare for All' backers notch win with high-profile hearing Here are the 95 Democrats who voted to support impeachment On The Money: Sanders unveils plan to wipe .6T in student debt | How Sanders plan plays in rivalry with Warren | Treasury watchdog to probe delay of Harriet Tubman bills | Trump says Fed 'blew it' on rate decision MORE (D), a member of the powerful House Ways and Means Committee, called the top House Democrat "aloof" in a statement explaining his decision to support a change in House leadership.

"She's listening, but this is my conclusion: She's aloof, frenetic and misguided," Higgins said earlier this month.

"I'm giving voice to a frustration that I hear every single day," he added. "It's members -- I don't want to call anybody out -- but this is the conversation that is taking place."