Senate Majority Leader (D-Nev.) is touting his Senate influence in his latest campaign ad.

The top Senate Democrat, who has looked vulnerable to a Republican challenger in 2010 in a series of opinion polls, is on-air in Nevada boasting of his clout in a 60-second TV ad.

"He's the most powerful senator Nevada has ever had, and Harry Reid's working harder than ever to get Nevada's economy back on track," the narrator in the ad says.

The ad lays out a number of projects Reid has helped obtain or preserve for his home state.

"America's most powerful senator," the ad concludes. "Harry Reid: Determination that makes a difference."

The ad goes on air as Reid's mettle as the top Senate Democrat is tested during a tumultuous debate over healthcare, where the majority leader is working diligently to bring all 60 members of his party onboard with legilslation.

Watch Reid's ad below: