Sen. Jim Bunning (R-Ky.) appears set to release blanket hold he had placed Tuesday on all of President Obama's nominees, according to Majority Leader Harry Reid's (D-Nev.) office. 

Bunning agreed tonight to end his blockade on extending unemployment benefits, but his decision to block all of the President's nominees is independent of that deal, according to Reid's office.

The Kentucky Republican, is the second senator this session to employ a blanket hold. Sen. Richard Shelby (R-Ala.) used the same tactic earlier this year in hopes of securing a defense appropriation for his home state. Shelby eventually relented.

Bunning's office was not available for comment.

Any senator can prevent a vote on a nominee by placing a hold, but the procedure is often used to block specific nominees, not all of them.