With news that Sen. George Voinovich (R) is not seeking re-election, Ohio immediately became a target for Democrats in 2010. And now it looks like a trio of Dems are jumping in the race.

The Associated Press reports that Ohio State Rep. Tyrone Yates is running for the Democratic nomination. He joins Secretary of State Jennifer Brunner and Lt. Gov. Lee Fisher on the Demcoratic side. Among Republicans, only former Congressman Rob PortmanRobert (Rob) Jones PortmanGOP ramps up attacks on SALT deduction provision Senate race in Ohio poses crucial test for Democrats Ohio Senate candidate unveils ad comparing Biden to Carter MORE has declared his candidacy.

Ohio flipped from red to blue in this year's presidential election with President Obama carrying in by a 51 percent to 47 percent margin (Bush carried it 51 percent to 49 percent over John KerryJohn KerryClimate policies propel a growing dysfunction of Western democracies Kerry calls out countries that need to 'step up' on climate change Those on the front lines of climate change should be empowered to be central to its solution MORE in 2004), giving Democrats an opportunity. But it'll be interesting to see if a crowded primary field clears the way for Portman on the GOP side.