Former Sen. Fred Thompson (R-Tenn.) said he's "concerned" about the relationship between President-elect Barack Obama, House Speaker Nancy Pelosi (D-Calif.) and Senate Majority Leader Harry Reid (D-Nev.).

"Oh, it will be a mess," Thompson said on Fox News's "Your World With Cavuto."

Thompson, a failed candidate for the 2008 GOP presidential nomination, praised Obama for his Cabinet appointments so far.