“We have not had a confirmed administrator since 2006,” Sen. Tim KaineTimothy (Tim) Michael KaineLiberty University professor charged with alleged sexual battery and abduction of student Senate parliamentarian looms over White House spending bill Menendez jabs State official over Colombian group's terror designation MORE (D-Va.) said ahead of the vote. “It will be a good thing for the mission and the country to confirm an administrator.”

Republican Sens. Ted CruzRafael (Ted) Edward CruzHospitals in underserved communities face huge cuts in reckless 'Build Back Better' plan To counter China, the Senate must confirm US ambassadors The Hill's Morning Report - Presented by Facebook - Congress avoids shutdown MORE (Texas), Ron JohnsonRonald (Ron) Harold JohnsonWisconsin senators ask outsiders not to exploit parade attack 'for their own political purposes' It's time to bury ZombieCare once and for all Marjorie Taylor Greene introduces bill to award Congressional Gold Medal to Rittenhouse MORE (Wis.), Mike LeeMichael (Mike) Shumway LeeThe Hill's Morning Report - Presented by Facebook - Congress avoids shutdown Senate dodges initial December crisis with last-minute deal Congress averts shutdown after vaccine mandate fight MORE (Utah), Mike CrapoMichael (Mike) Dean CrapoGOP ramps up attacks on SALT deduction provision Senate GOP threatens to block defense bill    Republican Senators request military aid for Taiwan amid pressure from China MORE (Idaho), James Risch (Idaho), Mitch McConnellAddison (Mitch) Mitchell McConnellDemocrats livid over GOP's COVID-19 attacks on Biden US could default within weeks absent action on debt limit: analysis The Hill's Morning Report - Presented by Facebook - Congress avoids shutdown MORE and Rand PaulRandal (Rand) Howard PaulRand Paul: Chris Cuomo firing 'a small step toward CNN regaining any credibility' GOP anger with Fauci rises Congress's goal in December: Avoid shutdown and default MORE (Ky.) voted against Tavenner's nominations.

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Sen. Tom HarkinThomas (Tom) Richard HarkinFCC needs to help services for the deaf catch up to videoconferencing tech Biden celebrates anniversary of Americans with Disabilities Act Ex-Rep. Abby Finkenauer running for Senate in Iowa MORE (D-Iowa) had placed a hold on her nomination out of frustration with the administration’s plan to spend prevention funds on promotions for the Affordable Care Act. He lifted the hold earlier this month after he said enough light had been shined on the issue.

CMS administers the Medicare and Medicaid programs and is also charged with implementing most of Obama's healthcare law. Tavenner has been leading CMS on an acting basis.

Kaine said Tavenner, who is from Virginia, was the right pick because she would bring a patient-focused “nurse’s attitude” to CMS and she is an “expert” on finding healthcare cost savings.

Before the vote on Tavenner, the Senate also voted to approve the nomination of William Orrick to be U.S. District Judge for the Northern District of California. He was confirmed on a 56-41 vote.

Sen. Barbara BoxerBarbara Levy BoxerFirst senator formally endorses Bass in LA mayoral bid Bass receives endorsement from EMILY's List Bass gets mayoral endorsement from former California senator MORE (D-Calif.) said she was glad Orrick got a vote because the Northern District of California has a judicial emergency with a caseload 24 percent higher than the national average.

“We all know justice delayed is justice denied,” Boxer said. “That’s why I’m excited we’re finally getting a vote on this nominee.”

Sen. Chuck GrassleyChuck GrassleyAlarm grows over smash-and-grab robberies amid holiday season GOP blocks bill to expand gun background checks after Michigan school shooting GOP ramps up attacks on SALT deduction provision MORE (R-Iowa) said he opposed Orrick's nomination because he  didn't like a judicial decision he made that maintained the “weak status quo” of immigration and border enforcement. He added that Orrick didn't answer all of his questions during his confirmation hearing with the Judiciary Committee, where Grassley serves as the ranking member.