Manchin says he will vote against DeVos

Sen. Joe ManchinJoseph (Joe) ManchinOn The Money: Cain 'very committed' to Fed bid despite opposition | Pelosi warns no US-UK trade deal if Brexit harms Irish peace | Ivanka Trump says she turned down World Bank job Cain says he won't back down, wants to be nominated to Fed Pro-life Christians are demanding pollution protections MORE (W.Va.) said Wednesday that he will oppose Betsy DeVos's nomination to lead the Department of Education.

Manchin — a Democrat from a red state who is up for reelection in 2018 — said he has "serious concerns" about President Trump's nominee.

"Every child in West Virginia deserves a quality education, and I do not believe that Betsy DeVos is qualified to serve in this role, which is so vital to the future of our state," he said.

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Manchin specifically pointed to DeVos's support for charter schools and the fact that she hasn't worked or attended a public school as key reasons for his opposition.

"The needs facing rural schools in West Virginia are unique, and her lack of exposure to public education is very concerning for me," he added.

DeVos could face a rocky path to confirmation. Republicans have a 52-seat majority, but two Republicans — Sens. Lisa MurkowskiLisa Ann MurkowskiCain says he 'won't run away from criticism' in push for Fed seat Cain says he won't back down, wants to be nominated to Fed License to discriminate: Religious exemption laws are trampling rights in rural America MORE (Alaska) and Susan CollinsSusan Margaret CollinsSenate Republicans tested on Trump support after Mueller Collins: Mueller report includes 'an unflattering portrayal' of Trump GOP senator: 'No problem' with Mueller testifying MORE (Maine) — have voiced reservations about supporting her nomination.

If Republicans were to defect on the confirmation vote, GOP leadership could need to flip red-state Democrats, like Manchin, to get DeVos confirmed.

Top Democrats, including Senate Minority Leader Charles SchumerCharles (Chuck) Ellis SchumerHillicon Valley: House Dems subpoena full Mueller report | DOJ pushes back at 'premature' subpoena | Dems reject offer to view report with fewer redactions | Trump camp runs Facebook ads about Mueller report | Uber gets B for self-driving cars Dem legal analyst says media 'overplayed' hand in Mueller coverage Former FBI official praises Barr for 'professional' press conference MORE (N.Y.), have come out against DeVos, and Sen. Al FrankenAlan (Al) Stuart FrankenWinners and losers from first fundraising quarter Election analyst says Gillibrand doesn't have 'horsepower to go the full distance' Gillibrand campaign links low fundraising to Al Franken backlash: memo MORE (D-Minn.) has predicted that no Democrats would support her.

Manchin said Trump's Education secretary needs to be someone "who has an understanding of the needs of all children, including those with disabilities, and is committed to ensuring they receive a quality education."