Senate Democrats blocked a proposal on Thursday that would crack down on cities that don't comply with federal immigration law.  

Senators voted 54-45 on the amendment from GOP Sen. Pat ToomeyPatrick (Pat) Joseph ToomeyBlack women look to build upon gains in coming elections Watch live: GOP senators present new infrastructure proposal Sasse rebuked by Nebraska Republican Party over impeachment vote MORE (R-Pa.) that would limit the flow of federal grants to the jurisdictions, commonly referred to as sanctuary cities.

Sixty votes were needed to overcome the procedural hurdle. 

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Democratic Sens. Joe DonnellyJoseph (Joe) Simon DonnellyBiden to have audience with pope, attend G20 summit Biden taps former Indiana Sen. Donnelly as ambassador to Vatican Republicans may regret restricting reproductive rights MORE (Ind.), Joe ManchinJoe ManchinOn The Money — Democrats craft billionaire tax with deal in reach Democrats face critical 72 hours Overnight Health Care — Presented by Altria — Manchin nixes Medicare expansion MORE (W.Va.), Claire McCaskillClaire Conner McCaskillEx-Rep. Akin dies at 74 Republicans may regret restricting reproductive rights Sunday shows preview: States deal with fallout of Ida; Texas abortion law takes effect MORE (Mo.) and Debbie StabenowDeborah (Debbie) Ann StabenowSenators weigh future of methane fee in spending bill Senate Democrats dial down the Manchin tension Democrats surprised, caught off guard by 'framework' deal MORE (Mich.) — who are each up for reelection in states won by Trump — supported the measure. 

“It is past time to act. Sanctuary city policies make it harder to stop illegal immigration and keep dangerous criminals off the streets,” Toomey said ahead of the vote. 

The amendment was widely expected to fall short. A similar bill failed 53-44 in 2016, when Republicans had a larger majority. 

McConnell tried to bring up Toomey's proposal for a vote on Tuesday but Democrats objected, arguing it was unrelated to fixing the Deferred Action for Childhood Arrivals (DACA) program.  

“The proposal he just offered does not address the underlying issues of this debate, why we’re here. It doesn’t address 'Dreamers' nor does it address border security,” Senate Minority Leader Charles SchumerChuck SchumerSenators weigh future of methane fee in spending bill Biden hopes for deal on economic agenda before Europe trip The Senate is setting a dangerous precedent with Iron Dome funding MORE (D-N.Y.) argued at the time. 

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Toomey's amendment is one of four senators are voting on Thursday. 

Senators already rejected a bipartisan immigration proposal from Sens. Chris CoonsChris Andrew CoonsBipartisan lawmakers target judges' stock trading with new bill Glasgow summit raises stakes for Biden deal Manchin threatens 'zero' spending in blowup with Sanders: reports MORE (D-Del.) and John McCainJohn Sidney McCainMeghan McCain to Trump: 'Thanks for the publicity' Grant Woods, longtime friend of McCain and former Arizona AG, dies at 67 Will Trump choose megalomania over country? MORE (R-Ariz.).  

They are also expected to vote on a bipartisan immigration-border security bill put forward by a gang of Senate centrists and the White House framework.