Lawmakers came out swinging (and singing) at the Washington Press Club Foundation’s 72nd annual Congressional Dinner on Thursday night — but they reserved some of their edgiest one-liners for the crop of 2016 presidential candidates.

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Sen. Lindsey GrahamLindsey Olin GrahamMSNBC's Joy Reid pans Manchin, Sinema as the 'no progress caucus' Overnight Defense: Biden proposes 3B defense budget | Criticism comes in from left and right | Pentagon moves toward new screening for extremists Biden defense budget criticized by Republicans, progressives alike MORE (S.C.), who exited the GOP presidential field in December, came out guns blazing despite saying he felt “like crap” as he battled illness and a hoarse voice.

Calling Hillary ClintonHillary Diane Rodham ClintonClose the avenues of foreign meddling Pelosi planned on retiring until Trump won election: report Pence autobiography coming from Simon & Schuster MORE the “most dishonest person in America,” Graham wondered aloud how the Democratic front-runner was “about to be the next president.”

“How could that be?” Graham asked the packed audience of hundreds of journalists, members of Congress and D.C. movers and shakers at Washington’s Mandarin Oriental Hotel. “My party has gone batshit crazy,” the senator answered to wild laughter.

Graham continued, aiming many of his quips toward his former fellow Oval Office contenders.

“A good Republican would defend Ted CruzRafael (Ted) Edward CruzBoehner: Trump 'stepped all over their loyalty' by lying to followers The Memo: Biden's five biggest foreign policy challenges Boehner finally calls it as he sees it MORE,” said Graham, of the Texas senator, before quickly adding, “that ain’t happening.”

“If you killed Ted Cruz on the floor of the Senate, and the trial was in the Senate, nobody could convict you,” Graham said, as the audience erupted in both laughter and some “oohs.”

House Minority Leader Nancy Pelosi (D-Calif.) also targeted Cruz during her turn at the mic, saying the Canada-born White House hopeful feels “right at home” at a “Justin Bieber concert, a Toronto Blue Jays baseball game, a maple syrup pitcher.”

She compared the Iowa caucuses winner to the Keystone XL pipeline: Both, she said, start in Alberta, end up in Texas and risk doing irreparable harm to the environment.

“There’s a special place in hell for women who do not laugh at my jokes tonight,” said Pelosi — referencing a controversial line former Secretary of State Madeleine Albright used at a Hillary Clinton rally.

Pelosi then began to repeat the same line again, before shuffling her notes, and saying, “Oh, I’m sorry, this is Marco RubioMarco Antonio RubioThe Memo: Biden's five biggest foreign policy challenges Hillicon Valley: Amazon wins union election — says 'our employees made the choice' Overnight Defense: Biden proposes 3B defense budget | Criticism comes in from left and right | Pentagon moves toward new screening for extremists MORE’s speech,” prodding the GOP presidential candidate for criticism that he’s too scripted.

Speaker Paul RyanPaul Davis RyanTrump faces test of power with early endorsements Lobbying world Boehner throws support behind Republican who backed Trump impeachment MORE (R-Wis.) got laughs while recalling two cases of mistaken identity.

After a woman approached him at a Milwaukee airport and asked for a photo, Ryan said she exclaimed, “Oh, it’s so nice to finally meet you, Gov. [Scott] Walker.”

In another instance at the same airport, Ryan says he encountered two flight attendants whispering to one another before telling him, “You’re somebody famous. Are you Anthony Weiner?”

Sen. Barbara BoxerBarbara Levy BoxerBottom line Trump administration halting imports of cotton, tomatoes from Uighur region of China Biden inaugural committee to refund former senator's donation due to foreign agent status MORE (D-Calif.) took some shots at both sides of the aisle, jesting that, at 75, she would soon be chairing Hillary Clinton’s “millennial outreach effort.”

Her next zinger had Republican presidential front-runner Donald TrumpDonald TrumpGaetz was denied meeting with Trump: CNN Federal Reserve chair: Economy would have been 'so much worse' without COVID-19 relief bills Police in California city declare unlawful assembly amid 'white lives matter' protest MORE’s name on it, with Boxer saying, “Trump’s been married so many times, he calls his current wife, ‘the incumbent.’” The retiring senator ended her set with a PG-rated song about appeasing television bookers and broadcasters, belting out a “West Side Story”-inspired tune called, “I Want to be on Your TV Show.”

Among the many lawmakers eyed at the annual festivities, which included a lively after-party sponsored by The Hill: Reps. Renee Ellmers (R-N.C.), Jim McGovern (D-Mass.), Debbie Dingell (D-Mich.), Billy Long (R-Mo.), Jim Jordan (R-Ohio), Diana DeGette (D-Colo.), Rick LarsenRichard (Rick) Ray LarsenDemocrats debate fast-track for infrastructure package LIVE COVERAGE: House votes to name Speaker COVID-19 is wild card as Pelosi faces tricky Speaker vote Sunday MORE (D-Wash.) Mac Thornberry (R-Texas), Mark Sanford (R-S.C.), Kevin McCarthy (R-Calif.) and David Brat (R-Va.) and Sen. Shelley Moore CapitoShelley Wellons Moore CapitoBiden-GOP infrastructure talks off to rocky start Moderate GOP senators and Biden clash at start of infrastructure debate America's infrastructure: You get what you pay for MORE (R-W.Va.).