Talk show host Oprah Winfrey is endorsing presumptive Democratic presidential nominee Hillary ClintonHillary Diane Rodham ClintonThe Armageddon elections to come Poll: Trump leads 2024 Republican field with DeSantis in distant second The politics of 'mind control' MORE.

“I’m with her,” she told Nancy O’Dell of "Entertainment Tonight" on Wednesday. "It’s a seminal moment for women. What this says is that there is no ceiling. That ceiling has gone ‘boom,’ you know?"

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Winfrey also said voters should and elect the nation’s first female president.

“America, it’s about time we made that decision,” she said in Los Angeles. "This is the truth. I really believe that that is going to happen.” 

Clinton earlier this month crossed the 2,382-delegate threshold needed to clinch the Democratic presidential nomination, becoming the first female presumptive nominee for a major political party.

Donald TrumpDonald TrumpNorth Korea conducts potential 6th missile test in a month Kemp leading Perdue in Georgia gubernatorial primary: poll US ranked 27th least corrupt country in the world MORE, Clinton's likely general election rival, said last year he would enthusiastically make Winfrey his running mate.

“I think Oprah would be great,” he told ABC News’s George Stephanopoulos. "I’d love to have Oprah. I think we’d win easily, actually.”

Winfrey said last year she would never launch her own Oval Office bid.

“I can tell you one thing you can be assured of in this lifetime: As long as I’m black, I will not be running for office,” she told “Extra” last year. "Never."