There was speculation in December of last year that Affleck would run for Senate in Massachusetts, to replace Secretary of State John KerryJohn Forbes KerrySeinfeld's Jason Alexander compares Trump dance video to iconic Elaine dance This time, for Democrats, Catholics matter President's job approval is surest sign Trump will lose reelection MORE. Affleck, a Boston native, and Kerry are close. The actor campaigned for Kerry's presidential campaign in 2004.

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But Affleck opted not to run and has seen his Hollywood career flourish: His film "Argo" won the Academy Award for Best Picture earlier this year.

Affleck has remained politically active through his Eastern Congo Initiative and he's testified on Capitol Hill about ending the war in the Congo. He also held a fundraiser for Massachusetts Democrat Elizabeth WarrenElizabeth WarrenWhat do Google, banks and chicken salad have in common? Final debate: War Admiral vs. Seabiscuit Biden defends his health plan from Trump attacks MORE's 2012 Senate campaign.

Garner said she would support her husband if he makes the political leap.

"I'm along for the ride," she told the magazine.