Ellen DeGeneres is defending Oprah Winfrey against President TrumpDonald TrumpEx-DOJ official Rosenstein says he was not aware of subpoena targeting Democrats: report Ex-Biden adviser says Birx told him she hoped election turned out 'a certain way' Cheney rips Arizona election audit: 'It is an effort to subvert democracy' MORE’s tweeted attacks, saying he’ll never “unite people” by going after the former talk show host.

“President Trump, it’s time for an a-ha moment,” DeGeneres says in a preview clip from the Thursday episode of “Ellen,” in which Winfrey appears as a guest.

“You’re not just some guy on Twitter anymore — you’re the president for all of us. It is your job to unite people, and you don’t do it by attacking people, especially Oprah,” DeGeneres says during her opening monologue.

“I mean, George Washington may be the father of our country, but Oprah is the mother of our country,” DeGeneres adds to applause.

DeGeneres’s remarks came after Trump slammed Winfrey in a Sunday tweet, calling the OWN founder and CBS “60 Minutes” special contributor “very insecure.”

Trump’s tweet came hours after a “60 Minutes” piece featuring Winfrey interviewing a group of Michigan voters about America’s political divide.

Winfrey publicly responds to Trump’s tweet for the first time during her appearance on “Ellen.”

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“I woke up and I just thought,” Winfrey exclaimed as she threw her hands up in the air with a puzzled expression.

“I don’t like giving negativity power so I just thought, what?” Winfrey added.

“I was working very hard to do the opposite of what I was hate-tweeted about,” she said.

The 64-year-old media mogul and "A Wrinkle in Time" star has has been floated as a possible 2020 White House contender after she delivered a rousing speech against sexual misconduct at last month’s Golden Globes, but she has denied any interest in a political bid.

DeGeneres, who’s criticized the president before, exclaims in her monologue that Trump had “gone too far” with the Winfrey criticism.

“Oprah is my friend, and when you mess with Oprah," she says, "you mess with me."