Filmmaker Rob Reiner slammed President TrumpDonald TrumpSenators given no timeline on removal of National Guard, Capitol fence Democratic fury with GOP explodes in House Georgia secretary of state withholds support for 'reactionary' GOP voting bills MORE on Thursday, claiming he is “aiding and abetting the enemy” in the "War against Isis" and "Cyberwar against Russia."

“Donald Trump is committing Treason against The United States of America,” Reiner tweeted Thursday. “He is aiding and abetting the enemy in The War against Isis and The Cyberwar against Russia."

"He has turned the world’s oldest Democracy into a wholly owned subsidiary of Vladimir Putin. GOP, WAKE UP!” he added.  

On Friday, Reiner claimed Trump is "mentally unstable" and accused the president of taking steps to "destroy" U.S. independence.

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"Each day this mentally unstable man takes a step closer to destroying 242 yrs. of self rule. And though Democrats want to be restrained, impeachment is inevitable," he tweeted.

"Then GOP Senators will have to make a choice. Either protect Democracy or continue to enable an ignorant criminal," he added. 

Reiner's comments came one day after Trump declared victory against ISIS in Syria and announced his administration's decision to withdraw troops from the nation.

The announcement drew bipartisan criticism, prompting a group of senators from both parties to send a letter to Trump on Wednesday asking him to reconsider his decision.

“If you decide to follow through with your decision to pull our troops out of Syria, any remnants of ISIS in Syria will surely renew and embolden their efforts in the region," they wrote. 

The senators, including  Lindsey GrahamLindsey Olin GrahamPassage of the John Lewis Voting Rights Advancement Act is the first step to heal our democracy Progressive support builds for expanding lower courts McConnell backs Garland for attorney general MORE (R-S.C.), Jeanne ShaheenCynthia (Jeanne) Jeanne ShaheenSenators press Treasury to prioritize Tubman redesign Can Palestine matter again? Senate signals broad support for more targeted coronavirus relief checks MORE (D-N.H.), Joni ErnstJoni Kay ErnstWe know how Republicans will vote — but what do they believe? The Hill's Morning Report - Presented by TikTok - Senate trial will have drama, but no surprise ending Overnight Defense: Pentagon says extremist groups 'very aggressively recruit' troops | Capitol Guard deployment estimated at 3M | No US combat deaths in Afghanistan for a year | VA secretary confirmed MORE (R-Iowa), Angus KingAngus KingBiden CIA pick pledges to confront China if confirmed, speak 'truth to power' Top cops deflect blame over Capitol attack Koch-backed group launches ads urging lawmakers to reject COVID-19 relief bill MORE (I-Maine), Tom CottonTom Bryant CottonRomney-Cotton, a Cancun cabbie and the minimum wage debate On The Money: Schumer urges Democrats to stick together on .9T bill | Collins rules out GOP support for Biden relief plan | Powell fights inflation fears Biden health nominee faces first Senate test MORE (R-Ark.) and Marco RubioMarco Antonio RubioRep. Stephanie Murphy says she's 'seriously considering' 2022 challenge to Rubio The Hill's Morning Report - Presented by The AIDS Institute - Finger-pointing on Capitol riot; GOP balks at Biden relief plan Sanders votes against Biden USDA nominee Vilsack MORE (R-Fla.), expressed concern that the decision would bolster Russian influence in the region. 

"As you are aware, both Iran and Russia have used the Syrian conflict as a stage to magnify their influence in the region," the senators added. "Any sign of weakness perceived by Iran or Russia will only result in their increased presence in the region and a decrease in the trust of our partners and allies."

Reiner has been a frequent critic of Trump, often taking to Twitter to lambast the president.

Reiner has called for Americans to increase their protests against the president, saying in June that he didn't think there was a "line" that could be crossed when it came to demonstrating against Trump.