Stephen ColbertStephen Tyrone ColbertScorned and mistreated, Melania Trump deserved much better from the media Biden sworn in on family Bible his son Beau used Can the GOP break its addiction to show biz? MORE argues President TrumpDonald TrumpMore than two-thirds of Americans approve of Biden's coronavirus response: poll Sarah Huckabee Sanders to run for governor Mexico's president tests positive for COVID-19 MORE wants to live detached from reality and is attempting to coax Americans into his "madness."

"Our president wants to live in a fantasy world where only the way he perceives the world is the way it is," the "Late Show" host told CNN's Anderson Cooper in an excerpt from a wide-ranging interview set to air Thursday on "Anderson Cooper 360."

"He's also trying to convince us that that is the only world that exists," Colbert, who frequently takes on Trump on his CBS late-night show, told Cooper when asked about him labeling the commander in chief a "heretic to reality."

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"It's extremely solipsistic," Colbert, 55, continued. "But he's also trying to invite us into this madness that he has. And that is heresy against reality."

"That is proselytizing for the most selfish, and the most basic instincts that the American people — like all people — have. But he's not appealing to the better angels of our nature."

While Trump appeared as a guest on Colbert's show in 2015, the comedian said he wouldn't welcome him to the "Late Show" stage again.

"The quick answer would be no because it would be hard for me to be properly respectful of the office," Colbert replied, when asked if he'd have Trump back as a guest. "Because I think that he is so disrespectful of the office, it's very hard to perceive him as I would want to perceive a president, in terms of their status, their dignity, and their representation of the United States. So I think just for safety's sake it wouldn't be a good idea."