Ohio Sen. Rob PortmanRobert (Rob) Jones PortmanMurkowski undecided on Tanden as nomination in limbo Biden signs supply chain order after 'positive' meeting with lawmakers Trump backs former campaign adviser for Ohio Republican Party chair MORE's (R) retirement announcement is sparking calls for basketball great Lebron James to take a shot at his seat.

Portman said Monday that he wouldn't seek a third term in 2022, saying partisanship and the "increasingly polarized country" played a role in his decision.

Social media quickly began buzzing following Portman's announcement, with many users voicing their support for the Los Angeles Laker player to become Sen. James.

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The 36-year-old sports star and philanthropist, who was born in Akron, Ohio, and played 11 seasons for the Cleveland Cavaliers, has frequently weighed in on political and social justice issues and was a prominent critic of former President TrumpDonald TrumpSenators given no timeline on removal of National Guard, Capitol fence Democratic fury with GOP explodes in House Georgia secretary of state withholds support for 'reactionary' GOP voting bills MORE.

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A rep for James didn't return ITK's request for comment.

The four-time NBA champion, who launched his voting rights organization More Than a Vote in 2020, has shut down talk of a political run before.

"No, I'm not considering it," James said last year, after Houston Rockets player DeMarcus Cousins suggested he make a White House bid.