Biden points to historic nature of 'madame vice president' — 'It's about time'
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President BidenJoe BidenPredictions of disaster for Democrats aren't guarantees of midterm failure A review of President Biden's first year on border policy  Vilsack accuses China of breaking commitments in Trump-era trade deal MORE gave a nod to the history Vice President Harris made as the first woman to hold the office before launching into his first address before a joint session of Congress on Wednesday.

As he took to the dais in the House chamber, Biden acknowledged Speaker Nancy PelosiNancy PelosiPelosi says she's open to stock trading ban for Congress Manchin: Biden spending plan talks would start 'from scratch' Reps. Massie, Grijalva test positive for COVID-19 MORE (D-Calif.) sitting behind him.

He then smiled broadly as he addressed Harris, saying, "Madam vice president."

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"No president has ever said those words from this podium," Biden said.

"And it's about time," he added.

Biden turned around and applauded Harris, the country's first female vice president.

Harris, 56, is also the first Black person and the first person of South Asian descent to be elected vice president of the United States.