Ellen DeGeneres is ending her long-running daytime talk show next year, saying she knows “it’s time.”

“Ellen” will bow out in 2022 after 19 seasons, DeGeneres told The Hollywood Reporter on Tuesday.

“I just needed something to challenge me. And as great as this show is, and as fun as it is, it’s just not a challenge anymore,” DeGeneres, 63, said. “I need something new to challenge me.”

Ratings for DeGeneres’s show had taken a tumble in recent months following allegations last summer of a toxic workplace. The comedian apologized during her show’s monologue last year, saying her show was embarking on a “new chapter.”

The controversy, DeGeneres said Tuesday, “destroyed” her.

“I’d be lying if I said it didn’t. And it makes me really sad that there’s so much joy out there from negativity,” she said.

“It’s a culture now where there are just mean people, and it’s so foreign to me that people get joy out of that. Then, on the heels of it, there are allegations of a toxic workplace and, unfortunately, I learned that through the press,” DeGeneres said. “And at first I didn’t believe it because I know how happy everybody is here and how every guest talks about, ‘Man, you have a great place here. Of all the talk shows I’ve done, everyone here is so happy.’ That’s all I’ve ever heard.”

But, DeGeneres said, her plan at her last contract negotiation three years ago was to end the show — which debuted in 2003 — after its 19th season.

The Emmy Award winner — known for her celebrity interviews, “Be Kind” mantra and sometimes-wacky games and sketches — had increasingly weighed in on politics on her show when President Trump was in office.

DeGeneres, who had made history on her 1990s sitcom as the country’s first openly gay lead character, said in 2017 that she had banned the then-commander in chief from appearing on her show.

“He’s against everything that I stand for,” she said at the time.