Jill Biden on Lindsey Graham: 'We used to be great friends, and now he's changed'

Jill Biden, the wife of former Vice President Joe BidenJoe BidenJoe Biden lost his fastball — can he get it back before South Carolina? Where the 2020 Democrats stand on taxes Bloomberg hits Sanders supporters in new ad MORE, said Monday it was “hard” to continue considering Sen. Lindsey GrahamLindsey Olin GrahamSenate braces for fight over impeachment whistleblower testimony US defense chief says Taliban deal 'looks very promising' but not without risk Lawmakers wary as US on cusp of initial deal with Taliban MORE (R-S.C.) a friend amid his announcement that he intends to investigate her family.

"Well, you know, Lindsey — I don't know what happened to Lindsey. And we used to be great friends and friends with John McCainJohn Sidney McCainEleventh Democratic presidential debate to be held in Phoenix Moderate Democrats now in a race against the clock Biden on Graham's push for investigation: 'I don't know what happened' to him MORE," Biden said on CNN’s “New Day” Monday, referring to the late senator. "I mean, we traveled together with the Foreign Relations Committee. We've had dinner, you know, and now he's changed."

Asked by CNN’s John Berman if she still considers Graham a friend, Biden responded, "You know, it's hard when you, I don't know, consider somebody a friend and then they've said so many things, so many negative things. And it's — that's been a little hurtful."

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Graham, one of President TrumpDonald John TrumpRussian sanctions will boomerang States, cities rethink tax incentives after Amazon HQ2 backlash A Presidents Day perspective on the nature of a free press MORE’s most vocal allies in the Senate, has continued to refer to the former vice president as a friend even as he says Hunter Biden’s business dealings in Ukraine should be investigated.

"I think this is a defining moment in the Biden campaign. Joe Biden is truly a friend. ... I think he’s a good man. But what Hunter Biden did was wrong at every level," Graham told Fox News anchor Bret Baier in October. "I think what Hunter Biden did does not pass the smell test."

Joe Biden, who has repeatedly claimed during his presidential campaign that Republican senators would be willing to work with him as president, expressed frustration about Graham in November, telling CNN’s Don LemonDon Carlton LemonCNN's Toobin warns McCabe is in 'perilous condition' with emboldened Trump Yang congratulates Romney for 'voting his conscience and character' in convicting Trump Jill Biden on Lindsey Graham: 'We used to be great friends, and now he's changed' MORE, “I am disappointed, and quite frankly I'm angered, by the fact — he knows me; he knows my son; he knows there's nothing to this.”