Jill Biden on Lindsey Graham: 'We used to be great friends, and now he's changed'

Jill Biden, the wife of former Vice President Joe BidenJoe BidenWith VP pick, Biden can't play small ball in a long ball world Poll: Trump, Biden in dead heat in 2020 matchup Coronavirus pushes GOP's Biden-Burisma probe to back burner MORE, said Monday it was “hard” to continue considering Sen. Lindsey GrahamLindsey Olin GrahamSunday shows preview: Lawmakers, state governors talk coronavirus, stimulus package and resources as pandemic rages on Campaigns pivot toward health awareness as races sidelined by coronavirus UK Prime Minister Boris Johnson tests positive for coronavirus MORE (R-S.C.) a friend amid his announcement that he intends to investigate her family.

"Well, you know, Lindsey — I don't know what happened to Lindsey. And we used to be great friends and friends with John McCainJohn Sidney McCainJuan Williams: Biden's promises on women are a big deal Ernst calls for public presidential campaign funds to go to masks, protective equipment President Trump is right — Now's the time for 'all hands on deck' MORE," Biden said on CNN’s “New Day” Monday, referring to the late senator. "I mean, we traveled together with the Foreign Relations Committee. We've had dinner, you know, and now he's changed."

Asked by CNN’s John Berman if she still considers Graham a friend, Biden responded, "You know, it's hard when you, I don't know, consider somebody a friend and then they've said so many things, so many negative things. And it's — that's been a little hurtful."

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Graham, one of President TrumpDonald John TrumpWith VP pick, Biden can't play small ball in a long ball world Coronavirus hits defense contractor jobs Wake up America, your country doesn't value your life MORE’s most vocal allies in the Senate, has continued to refer to the former vice president as a friend even as he says Hunter Biden’s business dealings in Ukraine should be investigated.

"I think this is a defining moment in the Biden campaign. Joe Biden is truly a friend. ... I think he’s a good man. But what Hunter Biden did was wrong at every level," Graham told Fox News anchor Bret Baier in October. "I think what Hunter Biden did does not pass the smell test."

Joe Biden, who has repeatedly claimed during his presidential campaign that Republican senators would be willing to work with him as president, expressed frustration about Graham in November, telling CNN’s Don LemonDon Carlton LemonDo people think ill of Jeff Sessions merely based on the sound of his voice? CNN's Toobin warns McCabe is in 'perilous condition' with emboldened Trump Yang congratulates Romney for 'voting his conscience and character' in convicting Trump MORE, “I am disappointed, and quite frankly I'm angered, by the fact — he knows me; he knows my son; he knows there's nothing to this.”