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McCaskill responds to Blunt retiring: 'I will never run for office again'

Former Missouri Sen. Claire McCaskillClaire Conner McCaskillThe Hill's Morning Report - Presented by Uber - Jan. 6 commission vote delayed; infrastructure debate lingers into June Missouri Republicans move to block Greitens in key Senate race Democratic Kansas City, Mo., mayor eyes Senate run MORE (D) ruled out the possibility of running to replace Sen. Roy BluntRoy Dean BluntExcellence Act will expand mental health and substance use treatment access to millions Overnight Health Care: Takeaways on the Supreme Court's Obamacare decision | COVID-19 cost 5.5 million years of American life | Biden administration investing billions in antiviral pills for COVID-19 Five takeaways on the Supreme Court's Obamacare decision MORE (R-Mo.) on Monday after he announced that he would not seek reelection in 2022.

In a tweet shortly after Blunt's announcement, McCaskill said that she would not seek public office again. Following her 2018 defeat by Sen. Josh HawleyJoshua (Josh) David HawleyPence heckled with calls of 'traitor' at conservative conference Five takeaways on the Supreme Court's Obamacare decision Senate confirms Biden pick for No. 2 role at Interior MORE (R-Mo.), McCaskill took a job as a political analyst with MSNBC and NBC News.

"To all that are asking: thank you to the many who have said kind things. But I will never run for office again. Nope. Not gonna happen. Never. I am so happy I feel guilty sometimes," she tweeted.

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McCaskill's announcement came minutes after a similar remark made by Jason Kander, who previously served as a Democratic member of the Missouri state House as well as the state's secretary of state.

"Regarding the Senate in ‘22: Always nice to be asked. Thanks. My decision not to run was never about who I’d run against," Kander tweeted.

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"I’m the President of @VCP_HQ and we’re building campuses for vets around the USA," he added. "Love this work, don’t want a new job. I’ll campaign for the Dem nominee!"

Blunt's retirement raises the prospect of another potential seat pickup for Senate Democrats next year, though his seat has been held by Republicans since the late 1980s. He is the fifth Senate Republican to say he will not seek reelection in 2022.