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Maher mocks 2020 Democrats, implores Oprah to run: She is only 'sure-thing winner'

HBO's Bill MaherWilliam (Bill) MaherJuan Williams: Clyburn is my choice as politician of the year Bill Maher, Trump adviser Jenna Ellis spar over election results Carville predicts Biden will quickly be declared winner: 'Not going to be close' MORE implored Oprah WinfreyOprah Gail Winfrey2020's top political celebrity moments Michelle Obama named most admired woman for third straight year: poll Oprah sells most of her stake in OWN channel to Discovery MORE to run against President TrumpDonald TrumpIran convicts American businessman on spying charge: report DC, state capitals see few issues, heavy security amid protest worries Pardon-seekers have paid Trump allies tens of thousands to lobby president: NYT MORE in 2020 while expressing doubts about the current crop of 24 candidates on the Democratic side, arguing she is the only "sure-thing winner" for the opposition party. 

"I am telling you that at this particular moment in history, in this particular election year, she is the only candidate who is a sure-thing winner for the Democrats," Maher said Friday during his show "Real Time." 

"No pressure," the host added. 

Maher also noted the power of candidates who are stars in modern politics. 

"Never underestimate the power of being in people's living rooms for decades. That's what got Trump elected," Maher said. "This is now an as-seen-on-TV country." 

"There really is no underestimating the power of celebrity in modern American politics," he later explained. "It’s not the way it’s supposed to be be, it's not the way I’d like it to be, but we officially live in a post-literate, post-truth, star-f---er society, and this is going to be the dirtiest campaign ever."

Maher, 65, went on to laud Winfrey as the only Democrat who could pull male voters from Trump's staunchly loyal base. 

"If he’s fed up with Trump, I know he would vote for Oprah. Because he knows that if he doesn’t, his wife will never blow him again."

Maher also blasted embattled 2020 front-runner Joe BidenJoe BidenFear of insider attack prompts additional FBI screening of National Guard troops: AP Iran convicts American businessman on spying charge: report DC, state capitals see few issues, heavy security amid protest worries MORE, comparing him to a typewriter while teeing off on other top-tier candidates. 

"Young people look at him like a typewriter's running for president," Maher joked about the former vice president.

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He also referred to Sen. Elizabeth WarrenElizabeth WarrenBiden to tap Rohit Chopra to lead CFPB, Gensler for SEC chair: reports Biden tax-hike proposals face bumpy road ahead Porter loses seat on House panel overseeing financial sector MORE (D-Mass.) as "a three-syllable woman in a one-syllable country," he added.

As for Sen. Bernie SandersBernie SandersBiden tax-hike proposals face bumpy road ahead Senate Democrats leery of nixing filibuster 'Almost Heaven, West Virginia' — Joe Manchin and a 50-50 Senate MORE, Maher described him as "an American hero in my book, but he's another one who has his cardiologist on speed dial."

Maher also evaluated South Bend, Ind., Mayor Pete ButtigiegPete ButtigiegOn The Money: Retail sales drop in latest sign of weakening economy | Fast-food workers strike for minimum wage | US officials raise concerns over Mexico's handling of energy permits Buttigieg confirmation hearing slated for Thursday James Murdoch predicts 'a reckoning' for media after Capitol riot MORE's chances.

"We must ask the question 'Is America ready to be led by a gay teenager?'" he joked.

"This is not an open letter to Oprah. I know she isn't running," Maher concluded at the end of his closing monologue.

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"I'm just saying: I have Nate Silvered the shit out of this, and I am telling you that at this particular moment in history, in this particular election year, she is the only candidate who is a sure-thing winner for the Democrats. No pressure. I am just putting it out into the universe."

Silver is a statistician and the founder of FiveThirtyEight, which conducts deep data dives on everything from elections to baseball.

Maher, who celebrated his 500th "Real Time" episode Friday night, donated $1 million to former President Barack ObamaBarack Hussein ObamaBiden-Harris team unveils inauguration playlist Can the GOP break its addiction to show biz? The challenge of Biden's first days: staying focused and on message MORE's 2012 reelection campaign.