Roy Blunt won't run for Senate seat in 2022

Sen. Roy BluntRoy Dean BluntThe Hill's Morning Report - Will Schumer back down on his deadline? GOP fumes over Schumer hardball strategy Cybersecurity bills gain new urgency after rash of attacks MORE (Mo.), a member of GOP leadership, announced on Monday that he won't run for reelection in 2022 — marking the latest high-profile retirement for Senate Republicans.

“After 14 general election victories — three to county office, seven to the United States House of Representatives, and four statewide elections — I won’t be a candidate for reelection to the United States Senate next year," Blunt said in a video.

Blunt, 71, said that he will finish out his current term, which runs through 2022. Blunt was first elected to the Senate in 2010 and previously served 14 years in the House, where he was also a member of GOP leadership. 

ADVERTISEMENT

He's the fifth Senate Republican expected not to seek reelection next year.

Sens. Pat ToomeyPatrick (Pat) Joseph ToomeyBlack women look to build upon gains in coming elections Watch live: GOP senators present new infrastructure proposal Sasse rebuked by Nebraska Republican Party over impeachment vote MORE (R-Pa.), Rob PortmanRobert (Rob) Jones PortmanSunday shows preview: Bipartisan infrastructure talks drag on; Democrats plow ahead with Jan. 6 probe Key Biden ally OK with dropping transit from infrastructure package Frustration builds as infrastructure talks drag MORE (R-Ohio) and Richard ShelbyRichard Craig ShelbyNational Guard cancels trainings after Congress fails to reimburse for Capitol riot deployment This week: Senate faces infrastructure squeeze GOP seeks to make Biden synonymous with inflation MORE (R-Ala.) have all announced that they will retire at the end of their current term. Sen. Richard BurrRichard Mauze BurrBipartisan group says it's still on track after setback on Senate floor Bipartisan group to issue 'promising' statement on infrastructure path forward First responders shouldn't have to tackle tigers MORE (R-N.C.) has also previously indicated he won't run for reelection.

Sens. Chuck GrassleyChuck GrassleyThe Hill's Morning Report - Pelosi considers adding GOP voices to Jan. 6 panel Ex-Rep. Abby Finkenauer running for Senate in Iowa Six takeaways: What the FEC reports tell us about the midterm elections MORE (R-Iowa) and Ron JohnsonRonald (Ron) Harold JohnsonSunday shows preview: Bipartisan infrastructure talks drag on; Democrats plow ahead with Jan. 6 probe Democrats question GOP shift on vaccines The Hill's Morning Report - Pelosi considers adding GOP voices to Jan. 6 panel MORE (R-Wis.) haven't yet said if they will run for reelection.

Grassley, 87, has told reporters that he'll make a decision this fall. Johnson, who had previously made a vow to only run for two terms, said last week that leaving office after 2022 was "probably my preference now."

Republicans only need to pick up one seat next year to win back the majority. But they are defending a total of 20 seats, compared to 14 for Democrats, including two seats in states that President BidenJoe BidenTrump hails Arizona Senate for audit at Phoenix rally, slams governor Republicans focus tax hike opposition on capital gains change Biden on hecklers: 'This is not a Trump rally. Let 'em holler' MORE won: Pennsylvania and Wisconsin.

ADVERTISEMENT

Though Democrats have been able to historically win Senate seats in Missouri, the state has swung hard toward Republicans and will likely start out as a safe Republican seat. Sen. Josh HawleyJoshua (Josh) David HawleyAtlanta-area spa shootings suspect set to be arraigned Noem to travel to South Carolina for early voting event Competition laws could be a death knell for startup mergers and acquisitions MORE (R-Mo.) defeated the state's most recent Democratic senator, Claire McCaskillClaire Conner McCaskillGiuliani to stump for Greitens in Missouri McCaskill shares new July 4 family tradition: Watching Capitol riot video Joe Manchin's secret MORE, in 2018 and former President TrumpDonald TrumpTrump hails Arizona Senate for audit at Phoenix rally, slams governor Arkansas governor says it's 'disappointing' vaccinations have become 'political' Watch live: Trump attends rally in Phoenix MORE won nearly 57 percent of the vote last year.

Former Missouri Secretary of State Jason Kander, who came within three points of Blunt in 2016, indicated on Monday that he will not run for the seat.

"Regarding the Senate in ‘22: Always nice to be asked. Thanks. My decision not to run was never about who I’d run against. I’m the President of @VCP_HQ and we’re building campuses for vets around the USA. Love this work, don’t want a new job. I’ll campaign for the Dem nominee!" Kander tweeted shortly after Blunt's announcement.

McCaskill also took herself out of the running Monday, saying on Twitter that, "I will never run for office again."

Blunt's retirement marks the latest blow for the institutionalist wing of the Senate GOP caucus, which has lost several members in recent election cycles. Sens. Bob CorkerRobert (Bob) Phillips CorkerCheney set to be face of anti-Trump GOP How leaving Afghanistan cancels our post-9/11 use of force The unflappable Liz Cheney: Why Trump Republicans have struggled to crush her  MORE (Tenn.), Lamar AlexanderLamar AlexanderAuthorities link ex-Tennessee governor to killing of Jimmy Hoffa associate The Republicans' deep dive into nativism Senate GOP faces retirement brain drain MORE (Tenn.) and Pat RobertsCharles (Pat) Patrick RobertsBob Dole, Pat Roberts endorse Kansas AG Derek Schmidt for governor Ex-Sen. Cory Gardner joins lobbying firm Senate GOP faces retirement brain drain MORE (Kan.) — committee chairmen known for their ability to cut deals — have retired over the past two cycles.

ADVERTISEMENT

Shelby, Blunt, Portman and Burr are also all ranking members of Senate committees, with their decisions to retire likely to set off a game of musical chairs among Senate Republicans for the plum positions. Blunt's decision is a shift from as recently as late January, where he seemed to indicate that he was likely to run for reelection.

"I'm planning to run but I haven't made an announcement on that yet. I'll wait for my announcement to officially decide what I'm going to do," he told reporters at the time.

Updated at 12:05 p.m.