Since leaving the White House, she has been a guest scholar at the left-leaning Brookings Institution.
At Consonance Capital, she will join former colleagues Mitchell Blutt, Benjamin Edmands and Stephen McKenna, who worked together at the private equity division of JPMorgan Chase from 2001 to 2009.
Blutt and Edmands, co-founders of Consonance Capital Partners, both said they are excited to work with DeParle again.
“It is wonderful to be reunited with Nancy-Ann,” said Blutt, the firm's chief executive, said in a statement. “There is no other individual with her combination of healthcare policy and industry insight and private equity investing expertise.”
Edmands, Consonance Capital's managing partner and co-founder, called DeParle "one of the foremost experts on healthcare policy."
"I am thrilled to be partnering with Nancy-Ann again and working to find innovative healthcare businesses that drive efficiency, quality and value,” he said in a statement.
DeParle has tangled in healthcare issues for her entire career, including serving a post as the director of the Health Care Financing Administration, now known as the Centers for Medicare and Medicaid Services, under President Clinton.